PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35174445-5	2022	According to the data available, this is the first time that ALA-induced changes in AChE and monoamine levels in the prefrontal cortex and hippocampus (brain structures related to learning and memory) have been demonstrated in a Sco-induced rat model of AD type dementia.	Thioctic Acid	61-64	acetylcholinesterase	Rattus norvegicus	84-88	
29500983-7	2018	Furthermore, ALA decreased hepatic malondialdehyde contents while increased the glutathione peroxidase, catalase, superoxide dismutase and acetylcholinesterase activities.	Thioctic Acid	13-16	acetylcholinesterase	Rattus norvegicus	139-159	
23389664-5	2013	Pretreatment with alpha-lipoic acid ameliorated the state of oxidative stress and restored AchE to nearly control activity.	Thioctic Acid	18-35	acetylcholinesterase	Rattus norvegicus	91-95	
20584203-0	2011	Neuropharmacological effects of lipoic acid and ubiquinone on the mRNA level of interleukin-1beta and acetylcholinesterase activity in rat hippocampus after seizures.	Thioctic Acid	32-43	acetylcholinesterase	Rattus norvegicus	102-122	
20584203-1	2011	The purpose of this study was to investigate the neuroprotective effects of lipoic acid and ubiquinone on interleukin-1beta (IL-1beta) mRNA levels and acetylcholinesterase (AChE) activities in rat hippocampus after pilocarpine-induced seizures.	Thioctic Acid	76-87	acetylcholinesterase	Rattus norvegicus	151-171	
20730314-0	2010	Lipoic acid increases glutathione peroxidase, Na+, K+-ATPase and acetylcholinesterase activities in rat hippocampus after pilocarpine-induced seizures?	Thioctic Acid	0-11	acetylcholinesterase	Rattus norvegicus	65-85	
19669875-0	2010	Lipoic Acid increases hippocampal choline acetyltransferase and acetylcholinesterase activities and improvement memory in epileptic rats.	Thioctic Acid	0-11	acetylcholinesterase	Rattus norvegicus	64-84	
16706642-0	2006	Protective efficacy of alpha-lipoic acid on acetylcholinesterase activity in aged rat brain regions.	Thioctic Acid	23-40	acetylcholinesterase	Rattus norvegicus	44-64	
16706642-1	2006	The purpose of the present investigation was to measure the activity of acetylcholinesterase in discrete regions of young and aged rat brain before and after DL-alpha-lipoic acid supplementation.	Thioctic Acid	158-178	acetylcholinesterase	Rattus norvegicus	72-92	
16706642-6	2006	These results suggest that lipoic acid is effective in restoration of the activity of acetylcholinesterase in aged rats.	Thioctic Acid	27-38	acetylcholinesterase	Rattus norvegicus	86-106