PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35174445-5 2022 According to the data available, this is the first time that ALA-induced changes in AChE and monoamine levels in the prefrontal cortex and hippocampus (brain structures related to learning and memory) have been demonstrated in a Sco-induced rat model of AD type dementia. Thioctic Acid 61-64 acetylcholinesterase Rattus norvegicus 84-88 29500983-7 2018 Furthermore, ALA decreased hepatic malondialdehyde contents while increased the glutathione peroxidase, catalase, superoxide dismutase and acetylcholinesterase activities. Thioctic Acid 13-16 acetylcholinesterase Rattus norvegicus 139-159 23389664-5 2013 Pretreatment with alpha-lipoic acid ameliorated the state of oxidative stress and restored AchE to nearly control activity. Thioctic Acid 18-35 acetylcholinesterase Rattus norvegicus 91-95 20584203-0 2011 Neuropharmacological effects of lipoic acid and ubiquinone on the mRNA level of interleukin-1beta and acetylcholinesterase activity in rat hippocampus after seizures. Thioctic Acid 32-43 acetylcholinesterase Rattus norvegicus 102-122 20584203-1 2011 The purpose of this study was to investigate the neuroprotective effects of lipoic acid and ubiquinone on interleukin-1beta (IL-1beta) mRNA levels and acetylcholinesterase (AChE) activities in rat hippocampus after pilocarpine-induced seizures. Thioctic Acid 76-87 acetylcholinesterase Rattus norvegicus 151-171 20730314-0 2010 Lipoic acid increases glutathione peroxidase, Na+, K+-ATPase and acetylcholinesterase activities in rat hippocampus after pilocarpine-induced seizures? Thioctic Acid 0-11 acetylcholinesterase Rattus norvegicus 65-85 19669875-0 2010 Lipoic Acid increases hippocampal choline acetyltransferase and acetylcholinesterase activities and improvement memory in epileptic rats. Thioctic Acid 0-11 acetylcholinesterase Rattus norvegicus 64-84 16706642-0 2006 Protective efficacy of alpha-lipoic acid on acetylcholinesterase activity in aged rat brain regions. Thioctic Acid 23-40 acetylcholinesterase Rattus norvegicus 44-64 16706642-1 2006 The purpose of the present investigation was to measure the activity of acetylcholinesterase in discrete regions of young and aged rat brain before and after DL-alpha-lipoic acid supplementation. Thioctic Acid 158-178 acetylcholinesterase Rattus norvegicus 72-92 16706642-6 2006 These results suggest that lipoic acid is effective in restoration of the activity of acetylcholinesterase in aged rats. Thioctic Acid 27-38 acetylcholinesterase Rattus norvegicus 86-106