PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27402296-2 2016 RESULTS: By combining the lipoic acid structure with N-benzylpiperidine or N,N-dibenzyl(N-methyl)amine fragments, new multi-target directed ligands were obtained that act at three relevant targets in AD: sigma-1 receptor (sigma1R), beta-secretase-1 (BACE1) and acetylcholinesterase (AChE). Thioctic Acid 26-37 acetylcholinesterase (Cartwright blood group) Homo sapiens 261-281 27402296-2 2016 RESULTS: By combining the lipoic acid structure with N-benzylpiperidine or N,N-dibenzyl(N-methyl)amine fragments, new multi-target directed ligands were obtained that act at three relevant targets in AD: sigma-1 receptor (sigma1R), beta-secretase-1 (BACE1) and acetylcholinesterase (AChE). Thioctic Acid 26-37 acetylcholinesterase (Cartwright blood group) Homo sapiens 283-287