PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23238616-0 2013 Alpha-lipoic acid ameliorates oxidative stress by increasing aldehyde dehydrogenase-2 activity in patients with acute coronary syndrome. Thioctic Acid 0-17 aldehyde dehydrogenase 2 family member Homo sapiens 61-85 29249928-9 2017 We hypothesized that the beneficial effects of ALA on patients with Alzheimer"s disease may be associated with accelerated ALDH2-mediated FA detoxification and clearance. Thioctic Acid 47-50 aldehyde dehydrogenase 2 family member Homo sapiens 123-128 23380360-4 2013 Moreover, certain nutraceuticals, including taurine, pantethine, and lipoic acid, may have the potential to boost the activity of the mitochondrial isoform of aldehyde dehydrogenase, ALDH-2, accelerating conversion of acetaldehyde to acetate (which arguably has protective health effects). Thioctic Acid 69-80 aldehyde dehydrogenase 2 family member Homo sapiens 183-189 23238616-2 2013 Alpha-lipoic acid (alpha-LA), a natural dithiol compound with antioxidant properties, has been reported to increase ALDH2 activity in cultured cells. Thioctic Acid 0-17 aldehyde dehydrogenase 2 family member Homo sapiens 116-121 23238616-2 2013 Alpha-lipoic acid (alpha-LA), a natural dithiol compound with antioxidant properties, has been reported to increase ALDH2 activity in cultured cells. Thioctic Acid 19-27 aldehyde dehydrogenase 2 family member Homo sapiens 116-121 19346443-1 2009 Recent animal data suggest that reduced lipoic acid (LA) prevents oxidative inhibition of the nitrate bioactivating enzyme, the mitochondrial aldehyde dehydrogenase (ALDH-2), and that pentaerythritol tetranitrate (PETN) does not induce nitrate tolerance because of its intrinsic antioxidative properties, thereby preserving ALDH-2 activity. Thioctic Acid 40-51 aldehyde dehydrogenase 2 family member Homo sapiens 166-172 19492396-3 2009 Specifically, we have reversibly tagged alpha-lipoic acid with a triphenylphosphonium moiety that is cleaved by the physiologically contained mitochondrial aldehyde dehydrogenase (ALDH-2). Thioctic Acid 40-57 aldehyde dehydrogenase 2 family member Homo sapiens 180-186 19346443-1 2009 Recent animal data suggest that reduced lipoic acid (LA) prevents oxidative inhibition of the nitrate bioactivating enzyme, the mitochondrial aldehyde dehydrogenase (ALDH-2), and that pentaerythritol tetranitrate (PETN) does not induce nitrate tolerance because of its intrinsic antioxidative properties, thereby preserving ALDH-2 activity. Thioctic Acid 40-51 aldehyde dehydrogenase 2 family member Homo sapiens 324-330