PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30535447-11	2019	The CCl4-induced suppression of the AKT/mTOR pathway was additionally restored following treatment with ALA.	Thioctic Acid	104-107	mechanistic target of rapamycin kinase	Rattus norvegicus	40-44	
25530759-0	2014	Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway.	Thioctic Acid	0-17	mechanistic target of rapamycin kinase	Rattus norvegicus	84-88	
30275871-9	2018	ALA treatment significantly increased the levels of phosphorylated 5"-AMPK, SIRT1, and PGC-1alpha, as well as the levels of phosphorylated AKT, mTOR, and p70S6 kinase in OLETF-ALA rats compared with OLETF-C rats.	Thioctic Acid	0-3	mechanistic target of rapamycin kinase	Rattus norvegicus	144-148	
30275871-12	2018	ALA significantly upregulated the AMPK/SIRT1/PGC-1alpha and AKT/mTOR/p70S6K signaling pathways in OLETF rat skeletal muscle.	Thioctic Acid	0-3	mechanistic target of rapamycin kinase	Rattus norvegicus	64-68	
29432779-0	2018	The protective effect of alpha-lipoic acid against brain ischemia and reperfusion injury via mTOR signaling pathway in rats.	Thioctic Acid	25-42	mechanistic target of rapamycin kinase	Rattus norvegicus	93-97	
25366515-2	2014	Alpha-lipoic acid (alphaLA) has been well accepted as a weight-loss treatment, though there are limited studies on its effect on mTOR signaling in high-fat fed, obese rodents.	Thioctic Acid	0-17	mechanistic target of rapamycin kinase	Rattus norvegicus	129-133	
25366515-2	2014	Alpha-lipoic acid (alphaLA) has been well accepted as a weight-loss treatment, though there are limited studies on its effect on mTOR signaling in high-fat fed, obese rodents.	Thioctic Acid	19-26	mechanistic target of rapamycin kinase	Rattus norvegicus	129-133	
25530759-1	2014	The aim of this study was to investigate whether alpha lipoic acid (LA) regulates high glucose-induced mesangial cell proliferation and extracellular matrix production via mTOR/p70S6K/4E-BP1 signaling.	Thioctic Acid	49-66	mechanistic target of rapamycin kinase	Rattus norvegicus	172-176	
22067655-4	2011	In contrast, activation of AMPK by both AICAR and alpha-lipoic acid led to the phosphorylation of specific molecules that diminished both mTOR/p70S6K signaling and insulin resistance.	Thioctic Acid	50-67	mechanistic target of rapamycin kinase	Rattus norvegicus	138-142	
20682696-8	2010	Coincubation with the AMPK activators AICAR and alpha-lipoic acid substantially prevented all of those changes and increased the phosphorylation of specific sites of mTOR inhibitors raptor and tuberous sclerosis complex 2 (TSC2).	Thioctic Acid	48-65	mechanistic target of rapamycin kinase	Rattus norvegicus	166-170