PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34252510-9	2021	Exogenous ALA blocked oxidative stress by activating NRF2.	Thioctic Acid	10-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	53-57	
23295186-0	2013	Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline.	Thioctic Acid	21-32	nuclear factor, erythroid derived 2, like 2	Mus musculus	79-83	
34058234-0	2021	Protective effect of alpha-lipoic acid on bisphenol A-induced learning and memory impairment in developing mice: nNOS and keap1/Nrf2 pathway.	Thioctic Acid	21-38	nuclear factor, erythroid derived 2, like 2	Mus musculus	128-132	
34058234-8	2021	ALA altered the protein levels of nNOS and keap1/Nrf2 pathway affected by BPA.	Thioctic Acid	0-3	nuclear factor, erythroid derived 2, like 2	Mus musculus	49-53	
34058234-9	2021	Our results suggested that impairments of learning and memory caused by BPA was related to the damage of hippocampal synapses mediated by oxidative stress, and ALA protected learning and memory by reducing the oxidative stress induced by BPA through regulating the nNOS and keap1/Nrf2 pathway.	Thioctic Acid	160-163	nuclear factor, erythroid derived 2, like 2	Mus musculus	280-284	
32719431-0	2020	Anti-allergic rhinitis activity of alpha-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling.	Thioctic Acid	35-52	nuclear factor, erythroid derived 2, like 2	Mus musculus	102-106	
33181275-5	2021	The cochlear Nrf2 level increased in test mice, indicating that the ALA-NPs protected hearing via the antioxidant mechanism observed in vitro.	Thioctic Acid	68-71	nuclear factor, erythroid derived 2, like 2	Mus musculus	13-17	
33181275-6	2021	ALA-NPs effectively protected against acute hearing loss by activating the Nrf2/HO-1 pathway.	Thioctic Acid	0-3	nuclear factor, erythroid derived 2, like 2	Mus musculus	75-79	
33742689-6	2021	Fatty acid oxidation potential and activity of nuclear erythroid-related factor 2 (NRF2) of mouse secondary lymphoid tissues were improved by ALA supplementation.	Thioctic Acid	142-145	nuclear factor, erythroid derived 2, like 2	Mus musculus	47-81	
33742689-6	2021	Fatty acid oxidation potential and activity of nuclear erythroid-related factor 2 (NRF2) of mouse secondary lymphoid tissues were improved by ALA supplementation.	Thioctic Acid	142-145	nuclear factor, erythroid derived 2, like 2	Mus musculus	83-87	
32061150-4	2020	The present study aimed to investigate whether alpha-LA could reduce the toxicity of MCs induced in human hepatoma (HepG2), Bel7420 cells, and BALB/c mice by activating Nrf2 to regenerate GSH.	Thioctic Acid	47-55	nuclear factor, erythroid derived 2, like 2	Mus musculus	169-173	
31874366-7	2020	The relative expression levels of Nrf-2 and Tnf-RI/P-60 receptor (P <= 0.05) significantly increased in response to LPS, and treatment with ALA significantly reduced the relative expression of Tnf-RI/P-60.	Thioctic Acid	143-146	nuclear factor, erythroid derived 2, like 2	Mus musculus	34-39