PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32732978-1	2020	Alpha-lipoic acid (alpha-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate tolerance and diabetic animal model.	Thioctic Acid	0-17	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	77-82	
32732978-1	2020	Alpha-lipoic acid (alpha-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate tolerance and diabetic animal model.	Thioctic Acid	19-27	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	77-82	
32732978-6	2020	In molecular level, alpha-LA significantly restored ALDH2 activity and expression as well as increased the expression of a novel mitophagy receptor protein FUNDC1 in wild-type TAC mice.	Thioctic Acid	20-28	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	52-57	
32732978-7	2020	Besides, we confirmed that ALDH2 which was activated by alpha-LA governed the activation of Nrf1-FUNDC1 cascade.	Thioctic Acid	56-64	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	27-32	
32732978-0	2020	Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling.	Thioctic Acid	0-17	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	79-84	
29249928-3	2017	It has been shown that 1,2-dithiolane-3-pentanoic acid or alpha lipoic acid (ALA), a naturally occurring dithiol and antioxidant cofactor of mitochondrial alpha-ketoacid dehydrogenases, increases glutathione (GSH) content and FA metabolism by mitochondrial aldehyde dehydrogenase 2 (ALDH2) thus manifests a therapeutic potential beyond its antioxidant property.	Thioctic Acid	23-54	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	283-288	
29249928-3	2017	It has been shown that 1,2-dithiolane-3-pentanoic acid or alpha lipoic acid (ALA), a naturally occurring dithiol and antioxidant cofactor of mitochondrial alpha-ketoacid dehydrogenases, increases glutathione (GSH) content and FA metabolism by mitochondrial aldehyde dehydrogenase 2 (ALDH2) thus manifests a therapeutic potential beyond its antioxidant property.	Thioctic Acid	58-75	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	283-288	
29249928-3	2017	It has been shown that 1,2-dithiolane-3-pentanoic acid or alpha lipoic acid (ALA), a naturally occurring dithiol and antioxidant cofactor of mitochondrial alpha-ketoacid dehydrogenases, increases glutathione (GSH) content and FA metabolism by mitochondrial aldehyde dehydrogenase 2 (ALDH2) thus manifests a therapeutic potential beyond its antioxidant property.	Thioctic Acid	77-80	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	283-288	
29249928-4	2017	We suggested that ALA can contribute to a decrease in the FA content of mammals by acting on ALDH2 expression.	Thioctic Acid	18-21	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	93-98	
29249928-8	2017	After ALA administration in mice and in accordance with the increased content of brain ALDH2 mRNA, we detected increased ALDH2 activity in brain homogenates.	Thioctic Acid	6-9	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	87-92	
29249928-8	2017	After ALA administration in mice and in accordance with the increased content of brain ALDH2 mRNA, we detected increased ALDH2 activity in brain homogenates.	Thioctic Acid	6-9	aldehyde dehydrogenase 2, mitochondrial	Mus musculus	121-126