PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14975735-4 2004 Our data show that succinyl acetone-induced heme deficiency increases the protein levels of the tumor suppressor gene product p53 and CDK inhibitor p21, and decreases the protein levels of Cdk4, Cdc2, and cyclin D2. succinylacetone 19-35 cyclin dependent kinase 4 Homo sapiens 189-193