PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35222388-0 2022 A 4-Benzene-Indol Derivative Alleviates LPS-Induced Acute Lung Injury Through Inhibiting the NLRP3 Inflammasome. 4-benzene-indol 2-17 NLR family pyrin domain containing 3 Homo sapiens 93-98 35222388-10 2022 To summarize, this research indicated that the newly-discovered 4-benzene-indol derivative targets NLRP3 inflammasome signaling, which consequently alleviates sepsis-related ALI. 4-benzene-indol 64-79 NLR family pyrin domain containing 3 Homo sapiens 99-104 35222388-8 2022 The results showed that 4-benzene-indol derivative could not only suppress the activation of NLRP3 inflammasome both in vitro and alleviate LPS-induced ALI in vivo but also suppress the NLRP3 inflammasome in human myeloid leukemia mononuclear cells (THP-1) cell lines. 4-benzene-indol 24-39 NLR family pyrin domain containing 3 Homo sapiens 93-98 35222388-8 2022 The results showed that 4-benzene-indol derivative could not only suppress the activation of NLRP3 inflammasome both in vitro and alleviate LPS-induced ALI in vivo but also suppress the NLRP3 inflammasome in human myeloid leukemia mononuclear cells (THP-1) cell lines. 4-benzene-indol 24-39 NLR family pyrin domain containing 3 Homo sapiens 186-191