PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1395777-1 1992 To visualize ASM contraction in vitro, we measured changes in cross-sectional area and inner circumference of isolated porcine and human bronchi in response to acetylcholine or carbamylcholine chloride (Carbachol) using high-frequency ultrasound. Carbachol 177-201 H19 imprinted maternally expressed transcript Homo sapiens 13-16 33041794-10 2020 UCL 1684 reduced carbachol-evoked ASM contractions (>90%, IC50 0.43 muM), and calcium mobilization in rodent and human lung ASM cells. Carbachol 17-26 H19 imprinted maternally expressed transcript Homo sapiens 34-37 31411061-7 2019 By contrast, carbachol-induced contraction of the ASM derived from Pkd2SM-CKO mice was significantly reduced compared with that in wild-type mice. Carbachol 13-22 H19 imprinted maternally expressed transcript Homo sapiens 50-53 31411061-8 2019 In addition, relaxation of the carbachol-precontracted ASM by isoprenaline, a beta-adrenergic receptor agonist that acts through the cAMP/adenylyl cyclase pathway, was also significantly attenuated in Pkd2SM-CKO mice compared with that in wild-type mice. Carbachol 31-40 H19 imprinted maternally expressed transcript Homo sapiens 55-58