PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30872401-6	2019	The retinoic acid receptor analog acitretin, which up-regulates ADAM10, also promoted PrPC shedding and decreased AbetaO binding in the neuroblastoma cells and in human induced pluripotent stem cell (iPSC)-derived cortical neurons.	Acitretin	34-43	prion protein	Homo sapiens	86-90	
30872401-7	2019	Pretreatment with acitretin abolished activation of Fyn kinase and prevented an increase in reactive oxygen species caused by AbetaO binding to PrPC Besides blocking AbetaO binding and toxicity, acitretin also increased the nonamyloidogenic processing of APP.	Acitretin	18-27	prion protein	Homo sapiens	144-148	
30872401-7	2019	Pretreatment with acitretin abolished activation of Fyn kinase and prevented an increase in reactive oxygen species caused by AbetaO binding to PrPC Besides blocking AbetaO binding and toxicity, acitretin also increased the nonamyloidogenic processing of APP.	Acitretin	195-204	prion protein	Homo sapiens	144-148