PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10868946-3 2000 In particular, leptin-evoked vasorelaxation is impaired by nitric oxide synthase inhibition in aorta (delta% of maximal response: from 36 +/- 3 to 3 +/- 1, P < 0.01) and by endothelium-derived hyperpolarizing factor (EDHF) inhibition in mesenteric arteries (delta% of maximal response: from 30 +/- 5 to 7 +/- 2, P < 0.01), suggesting that vasorelaxation evoked by leptin is heterogeneous and related to the vascular bed. 1-hexadecyl-2-acetyl-glycero-3-phosphocholine 212-218 leptin Rattus norvegicus 15-21