PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17111347-4 2006 We show that uridine and ribose, the two defining features of RNA, are both necessary and sufficient for TLR7 stimulation, and that short single-stranded RNA (ssRNA) act as TLR7 agonists in a sequence-independent manner as long as they contain several uridines in close proximity. Ribose 25-31 toll like receptor 7 Homo sapiens 105-109 30102387-9 2018 Testing permutations of the nucleobase at ribose-methylated position 54 suggested that the extent of silencing and antagonism of the TLR7 response was governed by hydrogen patterns and lipophilic interactions of the nucleobase. Ribose 42-48 toll like receptor 7 Homo sapiens 133-137 28576825-4 2017 Ribose 2"-O-methylation is of particular importance and has been reported to antagonize TLR7/8 activation. Ribose 0-6 toll like receptor 7 Homo sapiens 88-92