PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17371247-5 2007 In brief, ectopic expression of hVps34 drives S6K1 activation, but only in the presence of AAs, and this effect is blocked by small interfering RNAs directed against hVps34. Amino Acids 91-94 phosphatidylinositol 3-kinase catalytic subunit type 3 Homo sapiens 32-38 17371247-6 2007 Moreover, stimulation of cells with AAs increases hVps34 activity, as indicated by the production of PI3P (phosphatidylinositol 3-phosphate). Amino Acids 36-39 phosphatidylinositol 3-kinase catalytic subunit type 3 Homo sapiens 50-56 18460336-4 2008 Here we show that AAs induce a rise in intracellular Ca(2+) ([Ca(2+)](i)), which triggers mTOR Complex 1 and hVps34 activation. Amino Acids 18-21 phosphatidylinositol 3-kinase catalytic subunit type 3 Homo sapiens 109-115