PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35604424-11 2022 5S-tolvaptan was selectively synthesized from ketone MOP-21826 by CBR1 with a substantially smaller reaction velocity compared to tolvaptan monohydroxylation by CYP3A4/5. 5s-tolvaptan 0-12 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 161-169