PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21576265-3	2011	This requires Dbp5 interaction with Nup159 in NPC cytoplasmic filaments and activation of Dbp5"s ATPase activity by Gle1 bound to inositol hexakisphosphate (IP(6)).	Phytic Acid	130-155	nucleoporin GLE1	Saccharomyces cerevisiae S288C	116-120	
17289581-4	2007	In budding yeast, recent work suggests that the DEAD-box helicase Dbp5 remodels mRNPs at the NPC cytoplasmic face by removing Mex67 and that the Dbp5 ATPase is activated by Gle1 and inositol hexaphosphate (IP(6)).	Phytic Acid	182-204	nucleoporin GLE1	Saccharomyces cerevisiae S288C	173-177	
18724935-3	2008	Gle1 is an essential, conserved mRNA export factor whose export function is dependent on the small molecule inositol hexakisphosphate (IP(6)).	Phytic Acid	108-133	nucleoporin GLE1	Saccharomyces cerevisiae S288C	0-4	
20371601-0	2010	Control of mRNA export and translation termination by inositol hexakisphosphate requires specific interaction with Gle1.	Phytic Acid	54-79	nucleoporin GLE1	Saccharomyces cerevisiae S288C	115-119	
28869701-0	2017	Nup42 and IP6 coordinate Gle1 stimulation of Dbp5/DDX19B for mRNA export in yeast and human cells.	Phytic Acid	10-13	nucleoporin GLE1	Saccharomyces cerevisiae S288C	25-29	
28869701-2	2017	As mRNPs exit the nuclear pore complex (NPC) in Saccharomyces cerevisiae, this remodeling occurs through activation of Dbp5 by inositol hexakisphosphate (IP6 )-bound Gle1.	Phytic Acid	127-152	nucleoporin GLE1	Saccharomyces cerevisiae S288C	166-170	
28869701-2	2017	As mRNPs exit the nuclear pore complex (NPC) in Saccharomyces cerevisiae, this remodeling occurs through activation of Dbp5 by inositol hexakisphosphate (IP6 )-bound Gle1.	Phytic Acid	154-157	nucleoporin GLE1	Saccharomyces cerevisiae S288C	166-170	
15459192-0	2004	Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway.	Phytic Acid	12-37	nucleoporin GLE1	Saccharomyces cerevisiae S288C	81-85	
15459192-1	2004	Production of inositol hexakisphosphate (IP6) by Ipk1, the inositol-1,3,4,5,6-pentakisphosphate 2-kinase, is required for Gle1-mediated mRNA export in Saccharomyces cerevisiae cells.	Phytic Acid	14-39	nucleoporin GLE1	Saccharomyces cerevisiae S288C	122-126	
15459192-1	2004	Production of inositol hexakisphosphate (IP6) by Ipk1, the inositol-1,3,4,5,6-pentakisphosphate 2-kinase, is required for Gle1-mediated mRNA export in Saccharomyces cerevisiae cells.	Phytic Acid	41-44	nucleoporin GLE1	Saccharomyces cerevisiae S288C	122-126	
15459192-10	2004	Additionally, the cytoplasmic production of IP6 by plasma membrane-anchored Ipk1 rescued a gle1-2 ipk1-4 synthetic lethal mutant.	Phytic Acid	44-47	nucleoporin GLE1	Saccharomyces cerevisiae S288C	91-95	
15459192-11	2004	Thus, cytoplasmic IP6 production is sufficient for mediating the Gle1-mRNA export pathway.	Phytic Acid	18-21	nucleoporin GLE1	Saccharomyces cerevisiae S288C	65-69	
10390371-4	1999	The common downstream effects of mutations in each component were deficiencies in IP6 synthesis and messenger RNA export, indicating a role for IP6 in GLE1 function and messenger RNA export.	Phytic Acid	144-147	nucleoporin GLE1	Saccharomyces cerevisiae S288C	151-155	
28869701-7	2017	Deletion of NUP42 abrogates Gle1-Dbp5 interaction, and disruption of the Nup42 or IP6 binding interfaces on Gle1/hGle1B leads to defective mRNA export in S. cerevisiae and human cells.	Phytic Acid	82-85	nucleoporin GLE1	Saccharomyces cerevisiae S288C	108-112