PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29111280-7	2019	Inositol pyrophosphates, synthesized by inositol hexakisphosphate (IP6) kinase 1 (IP6K1) and competitive with 3,4,5-bisphosphate (PIP3) to bind the PH domain of Akt/PKB, demonstrate the ability to inhibit Akt signaling.	Phytic Acid	40-65	thymoma viral proto-oncogene 1	Mus musculus	161-168	
29111280-7	2019	Inositol pyrophosphates, synthesized by inositol hexakisphosphate (IP6) kinase 1 (IP6K1) and competitive with 3,4,5-bisphosphate (PIP3) to bind the PH domain of Akt/PKB, demonstrate the ability to inhibit Akt signaling.	Phytic Acid	40-65	thymoma viral proto-oncogene 1	Mus musculus	161-164	
28962394-8	2015	IP6 administration also inhibited the activation of Akt and cyclin D1.	Phytic Acid	0-3	thymoma viral proto-oncogene 1	Mus musculus	52-55	
34969251-8	2022	Mechanism studies showed that PA exerted an anti-MIR effect by inhibiting the AKT/NF-kappaB signaling pathway.	Phytic Acid	30-32	thymoma viral proto-oncogene 1	Mus musculus	78-81	
30806292-9	2019	IP6-fed F1 mice showed reduced tumorigenesis along with reduced expression of the PI3K/Akt pathway miR-21 and downstream targets.	Phytic Acid	0-3	thymoma viral proto-oncogene 1	Mus musculus	87-90	
30806292-10	2019	The PI3K/Akt pathway and miR-21 are involved in transplacental lung tumorigenesis, whereas IP6 seemed to affect lung tumorigenesis by suppressing the expression of the PI3K/Akt pathway in F1 mice.	Phytic Acid	91-94	thymoma viral proto-oncogene 1	Mus musculus	173-176	
24847908-2	2014	IP6K inhibition may increase Akt activation in mesenchymal stem cells (MSCs), resulting in enhanced cardiac protective effect after transplantation.	Phytic Acid	0-3	thymoma viral proto-oncogene 1	Mus musculus	29-32