PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26385515-5 2015 Additionally, the divalent cations Ca(2+) and Mg(2+) influenced the IP6-induced distribution of occludin, ZO-1, and claudin-1 in different directions, which enhanced barrier function. Phytic Acid 68-71 tight junction protein 1 Homo sapiens 106-110 26385515-3 2015 Confocal microscopy results showed that IP6 produced a concentration-dependent attenuation in the distribution of occludin, ZO-1, and claudin-1. Phytic Acid 40-43 tight junction protein 1 Homo sapiens 124-128 26385515-6 2015 In conclusion, IP6 can decrease the integrity of Caco-2 cell monolayers by modulating the TJ proteins" localization and down-regulating the expression levels of TJ proteins including claudin-1, occludin, and ZO-1; the reduction effects of divalent cations such as Ca(2+) and Mg(2+) on the regulation of TJ induced by IP6 should be addressed. Phytic Acid 15-18 tight junction protein 1 Homo sapiens 208-212