PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21050017-2 2010 Here we report the first successful use of solution NMR in mapping the binding sites in arrestin-1 (visual arrestin) for two polyanionic compounds that mimic phosphorylated light-activated rhodopsin: inositol hexaphosphate (IP6) and heparin. Phytic Acid 200-222 S-antigen visual arrestin Homo sapiens 88-98 21050017-2 2010 Here we report the first successful use of solution NMR in mapping the binding sites in arrestin-1 (visual arrestin) for two polyanionic compounds that mimic phosphorylated light-activated rhodopsin: inositol hexaphosphate (IP6) and heparin. Phytic Acid 224-227 S-antigen visual arrestin Homo sapiens 88-98 21050017-4 2010 IP6 and heparin appear to bind to the same site on arrestin-1, centered on a positively charged region in the N-domain. Phytic Acid 0-3 S-antigen visual arrestin Homo sapiens 51-61 18161994-0 2008 Opposing effects of inositol hexakisphosphate on rod arrestin and arrestin2 self-association. Phytic Acid 20-45 S-antigen visual arrestin Homo sapiens 49-61 18161994-6 2008 In contrast to arrestin2, IP6 inhibits self-association of rod arrestin, indicating that the structure of these two tetramers in solution is likely different. Phytic Acid 26-29 S-antigen visual arrestin Homo sapiens 59-71