PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22905230-4 2012 On one hand, we show that IP6 decreases the osteoclastogenesis in RAW 264.7 cells induced by RANKL, without affecting cell proliferation or cell viability. Phytic Acid 26-29 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 93-98 23221481-6 2012 Besides, Rankl mRNA levels were decreased after IP6 treatment in MC3T3-E1 cells, pointing to a paracrine effect on osteoclasts. Phytic Acid 48-51 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 9-14 22905230-5 2012 The number of TRAP positive cells and mRNA levels of osteoclast markers such as TRAP, calcitonin receptor, cathepsin K and MMP-9 was decreased by IP6 on RANKL-treated cells. Phytic Acid 146-149 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 153-158 22905230-6 2012 On the contrary, when giving IP6 to mature osteoclasts after RANKL treatment, a significant increase of bone resorption activity and TRAP mRNA levels was found. Phytic Acid 29-32 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 61-66