PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27047482-0 2016 Translational Inhibition of CTX-M Extended Spectrum beta-Lactamase in Clinical Strains of Escherichia coli by Synthetic Antisense Oligonucleotides Partially Restores Sensitivity to Cefotaxime. Oligonucleotides 130-146 beta-lactamase Escherichia coli 52-66 27047482-4 2016 These antisense oligonucleotides were found to inhibit beta-lactamase activity by up to 96% in a cell-free translation-transcription coupled system using an expression vector carrying a bla CTX-M-15 gene cloned from a clinical isolate. Oligonucleotides 16-32 beta-lactamase Escherichia coli 55-69 1841655-4 1991 Escherichia coli transformed with a plasmid containing the gene for beta-lactamase were used to test a series of oligonucleotides containing psoralen monoadducts after additional exposure to the photoactivating effects of long-wavelength ultraviolet radiation (320-400 nm). Oligonucleotides 113-129 beta-lactamase Escherichia coli 68-82 3108235-1 1987 Oligonucleotide-directed mutagenesis of the beta-lactamase gene, bla, on pBR322 was used to change the codon for the active-site serine 70, AGC, to CGC, coding for arginine. Oligonucleotides 0-15 beta-lactamase Escherichia coli 44-58