PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11516649-7	2001	Moreover, treatment of cells with butan-1-ol or phospholipase D1 antisense oligonucleotides inhibits translocation of PKCdelta, -epsilon, and -zeta but had no effect on the association of PKCalpha or ARF6 with phospholipase D1.	Oligonucleotides	75-91	phospholipase D1	Homo sapiens	48-64	
18424723-7	2008	Using antisense oligonucleotides to reduce specifically the expression of PLD isozymes showed PLD1, but not PLD2, to be coupled to TNF-alpha signaling and that PLD1 is required to mediate receptor activation of sphingosine kinase and calcium transients.	Oligonucleotides	16-32	phospholipase D1	Homo sapiens	94-98	
18424723-9	2008	Furthermore, use of antisense oligonucleotides to reduce expression of PLD1 or PLD2 demonstrated that PLD1 is required for TNF-alpha-induced production of several important cytokines, such as IL-1beta, IL-5, IL-6, and IL-13, in human monocytes.	Oligonucleotides	30-46	phospholipase D1	Homo sapiens	71-75	
18424723-9	2008	Furthermore, use of antisense oligonucleotides to reduce expression of PLD1 or PLD2 demonstrated that PLD1 is required for TNF-alpha-induced production of several important cytokines, such as IL-1beta, IL-5, IL-6, and IL-13, in human monocytes.	Oligonucleotides	30-46	phospholipase D1	Homo sapiens	102-106	
12270129-6	2002	In cells transiently permeabilized with streptolysin-O, antisense oligonucleotides directed against PLD1 or 2 entered the cytoplasm as shown by immunofluorescence experiments but did not affect astroglial proliferation within 2-6 days.	Oligonucleotides	66-82	phospholipase D1	Homo sapiens	100-104	
11719383-5	2001	With the use of antisense oligonucleotides to specifically reduce the expression of either isozyme, PLD1, but not PLD2, was found to be coupled to FcgammaRI activation and be required to mediate receptor activation of sphingosine kinase and calcium transients.	Oligonucleotides	26-42	phospholipase D1	Homo sapiens	100-104	
11719383-7	2001	Furthermore, use of antisense oligonucleotides to reduce expression of PLD1 or PLD2 demonstrated that PLD1 is required to couple FcgammaRI to the activation of NADPH oxidase and trafficking of internalized immune complexes for degradation.	Oligonucleotides	30-46	phospholipase D1	Homo sapiens	71-75	
11719383-7	2001	Furthermore, use of antisense oligonucleotides to reduce expression of PLD1 or PLD2 demonstrated that PLD1 is required to couple FcgammaRI to the activation of NADPH oxidase and trafficking of internalized immune complexes for degradation.	Oligonucleotides	30-46	phospholipase D1	Homo sapiens	102-106	
11516649-7	2001	Moreover, treatment of cells with butan-1-ol or phospholipase D1 antisense oligonucleotides inhibits translocation of PKCdelta, -epsilon, and -zeta but had no effect on the association of PKCalpha or ARF6 with phospholipase D1.	Oligonucleotides	75-91	phospholipase D1	Homo sapiens	210-226