PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20351780-3 2010 Selective loss or blockade of cytosolic Hsp60 by specific antisense oligonucleotide or neutralizing antibody diminished the IKK/NF-kappaB activation and the expression of NF-kappaB target genes, such as Bfl-1/A1 and MnSOD, which thus augmented intracellular ROS production and ASK1-dependent cell death, in response to TNF-alpha. Oligonucleotides 68-83 heat shock protein 1 (chaperonin) Mus musculus 40-45 11086048-5 2000 Moreover, both the pcDNA3 vector and the CpG oligonucleotide induced specific Abs, primarily of the IgG2b isotype, to HSP60 and p277, and not to other islet Ags (glutamic acid decarboxylase or insulin) or to an unrelated recombinant Ag expressed in bacteria (GST). Oligonucleotides 45-60 heat shock protein 1 (chaperonin) Mus musculus 118-123 10602674-9 1999 To determine the function of HSP65, macrophages were treated in vitro with antisense oligonucleotide for HSP65 prior to inducing HSP65 with IFN-gamma plus TNF-alpha or T. cruzi infection. Oligonucleotides 85-100 heat shock protein 1 (chaperonin) Mus musculus 105-110 10602674-9 1999 To determine the function of HSP65, macrophages were treated in vitro with antisense oligonucleotide for HSP65 prior to inducing HSP65 with IFN-gamma plus TNF-alpha or T. cruzi infection. Oligonucleotides 85-100 heat shock protein 1 (chaperonin) Mus musculus 105-110 9278328-8 1997 However, apoptosis associated with infection by T. gondii RH strain was not prevented when HSP65 synthesis was inhibited by introducing an antisense oligonucleotide for this protein into the cells before activation with IFN-gamma plus TNF-alpha. Oligonucleotides 149-164 heat shock protein 1 (chaperonin) Mus musculus 91-96 7875208-4 1995 Based on our observation that lysis of stressed target cells by this cytotoxic T lymphocyte (CTL) clone was specifically inhibited by hsp60-specific antisense oligonucleotides, we used synthetic peptides representing amino acid (aa) sequences of the murine hsp60 for target cell sensitization and identification of the relevant self peptide. Oligonucleotides 159-175 heat shock protein 1 (chaperonin) Mus musculus 134-139