PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2174104-6 1990 A synthetic oligonucleotide corresponding to this binding site, as well as a similar sequence found in another class III complement C4 gene, conferred IL-1 responsiveness on the minimal factor B promoter. Oligonucleotides 12-27 interleukin 1 complex Mus musculus 151-155 10759763-4 2000 When antisense oligonucleotide was given on day 0, the disease activity index (DAI) representing clinical symptoms improved and the histological score decreased; furthermore, IL-1, IL-6, and TNF-alpha concentrations in rectal mucosa were lower compared with the control group. Oligonucleotides 15-30 interleukin 1 complex Mus musculus 175-179 8325323-10 1993 Binding of IL-1 NF to the TCEd site was competed by a typical chi B oligonucleotide, suggesting that it is similar to NF-chi B in its DNA-binding properties. Oligonucleotides 68-83 interleukin 1 complex Mus musculus 11-15 1833422-2 1991 Murine antisense oligonucleotides inhibited IL-1-stimulated PGE2 synthesis by murine fibroblasts in culture in a time (days) and concentration-dependent (3 microM-30 microM) fashion. Oligonucleotides 17-33 interleukin 1 complex Mus musculus 44-48 1833422-5 1991 Similarly, antisense oligonucleotides to the human, but not the murine, IL-1 receptor inhibited IL-1-stimulated PGE2 synthesis by cultured human fibroblasts. Oligonucleotides 21-37 interleukin 1 complex Mus musculus 96-100 1833422-6 1991 The attenuation of the cellular response to IL-1 caused by the antisense oligonucleotides correlated with a loss in cell surface receptors for IL-1, without any change in the number of bradykinin receptors on these cells. Oligonucleotides 73-89 interleukin 1 complex Mus musculus 44-48 1833422-6 1991 The attenuation of the cellular response to IL-1 caused by the antisense oligonucleotides correlated with a loss in cell surface receptors for IL-1, without any change in the number of bradykinin receptors on these cells. Oligonucleotides 73-89 interleukin 1 complex Mus musculus 143-147 1833422-7 1991 When antisense oligonucleotides were encapsulated in liposomes, they blocked completely the appearance of newly synthesized IL-1 receptors and IL-1-stimulated PGE2 synthesis. Oligonucleotides 15-31 interleukin 1 complex Mus musculus 124-128 1833422-7 1991 When antisense oligonucleotides were encapsulated in liposomes, they blocked completely the appearance of newly synthesized IL-1 receptors and IL-1-stimulated PGE2 synthesis. Oligonucleotides 15-31 interleukin 1 complex Mus musculus 143-147 1833422-8 1991 In mice, subcutaneous injection with an oligonucleotide antisense to the murine IL-1 receptor markedly inhibited the infiltration of neutrophils in response to subsequent injection of IL-1. Oligonucleotides 40-55 interleukin 1 complex Mus musculus 80-84 1833422-8 1991 In mice, subcutaneous injection with an oligonucleotide antisense to the murine IL-1 receptor markedly inhibited the infiltration of neutrophils in response to subsequent injection of IL-1. Oligonucleotides 40-55 interleukin 1 complex Mus musculus 184-188 7877456-6 1994 Oligonucleotide probes were then synthesized and used in RT-PCR followed by Southern blotting to show that the whole brain expresses transcripts for both the type I and type II IL-1 receptors. Oligonucleotides 0-15 interleukin 1 complex Mus musculus 177-181 1978316-6 1990 Addition to AtT-20 cells of antisense oligonucleotides to Fos and Jun abolished the secretion induced by IL-1. Oligonucleotides 38-54 interleukin 1 complex Mus musculus 105-109