PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17762649-5 2007 The PKC inhibitor antagonized angiotensin II-induced p47 phosphorylation, and an antisense oligonucleotide (ASON) complementary to PKCbeta messenger RNA suppressed angiotensin II-induced ERK1/2 activation, phosphorylation or DNA binding activity of CREB, and upregulation of c-fos mRNA expression in the ventrolateral medulla. Oligonucleotides 91-106 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 275-280 11747755-5 2001 Intrathecal injection of nNOS antisense oligonucleotides (nNOS-AS) inhibited the increase of Fos protein and NMDA(1A)R mRNA expression in the rat spinal cord during morphine withdrawal and decreased the scores of morphine withdrawal symptoms. Oligonucleotides 40-56 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 93-96 15804434-6 2005 In addition, the PMA-induced c-fos gene expression was inhibited by PKCbetaantisense oligonucleotides (AON) but not by PKCalpha and PKCgammaAONs. Oligonucleotides 85-101 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 29-34 15053967-0 2004 c-fos antisense oligonucleotides increase firing rate of striatal neurons in the anaesthetized rat. Oligonucleotides 16-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-5 12716432-8 2003 The c-fos induction kinetically corresponded to the Elk-1 phosphorylation and was attenuated by antisense oligonucleotides that selectively knocked down Elk-1 proteins. Oligonucleotides 106-122 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 4-9 12670703-7 2003 The complexes formed with labeled AP1/E box oligonucleotide were reduced or supershifted with antisera to Fos family, c-Fos, Fra-2, and Jun D. Oligonucleotides 44-59 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 106-109 12670703-7 2003 The complexes formed with labeled AP1/E box oligonucleotide were reduced or supershifted with antisera to Fos family, c-Fos, Fra-2, and Jun D. Oligonucleotides 44-59 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 118-123 12617307-1 2003 In situ hybridization using oligonucleotide probes was used to study the effects of intrastriatal microinjection of corticoliberin on the expression of the early genes c-fos, jun B, c-jun, and NGFIA in the rat brain. Oligonucleotides 28-43 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 168-173 11788392-8 2002 PYK2 downregulation with antisense oligonucleotides blocked ANG II-induced c-Fos expression. Oligonucleotides 35-51 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 75-80 11790521-6 2002 Inhibition of Fos expression in this region of the hippocampus, but not the cingulate and motor cortex, by means of antisense oligonucleotide treatment resulted in an impairment of spatial memory formation. Oligonucleotides 126-141 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 14-17 11463773-4 2001 Both the suppression of spontaneous baroreceptor reflex and Fos expression in nucleus tractus solitarii neurons elicited by Ang II were discernibly attenuated by pretreatment with or comicroinjection into the bilateral nucleus tractus solitarii of a 15-mer antisense c-fos oligonucleotide that targets against the initiation codon of c-fos mRNA. Oligonucleotides 273-288 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 60-63 16140209-6 2005 Pretreatment of PC12 cells with c-fos antisense oligonucleotide abolished the NO-induced increase in DNA binding of AP-1 and upregulation of COX-2 expression. Oligonucleotides 48-63 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 32-37 15829701-9 2005 In SOCS-3 knockdown studies, antisense oligonucleotides inhibited the expression of SOCS-3 and increased the Ang II-induced STAT activation and c-Fos/c-Jun expression, then resulting in a more severe renal damage. Oligonucleotides 39-55 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 144-149 16044914-0 2005 [Intrathecal injection of muscarinic receptors or GDNF antisense oligonucleotides inhibits the increase of c-Fos expression in locus coeruleus of morphine-withdrawal rats]. Oligonucleotides 65-81 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 107-112 12558986-10 2003 The increase in c-fos was kinetically correlated well with the CREB phosphorylation and blocked by MPEP and the CREB antisense oligonucleotides. Oligonucleotides 127-143 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 16-21 12215476-6 2002 Whereas the re-expression of AT1R at both transcriptional and functional expression levels after baroreceptor activation was discernibly blunted by prior bilateral application into the NTS of an antisense c-fos oligonucleotide (50 pmol), the suppression in SHR was again significantly more intense. Oligonucleotides 211-226 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 205-210 12215476-7 2002 Control pretreatment with the corresponding sense or scrambled c-fos oligonucleotide was ineffective. Oligonucleotides 69-84 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 63-68 11786972-6 2002 Finally, Fos expression in the nucleus tractus solitarius (NTS) was blocked by local microinjection of c-fos antisense oligonucleotides twice daily for 5 days following PVS. Oligonucleotides 119-135 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 9-12 11786972-6 2002 Finally, Fos expression in the nucleus tractus solitarius (NTS) was blocked by local microinjection of c-fos antisense oligonucleotides twice daily for 5 days following PVS. Oligonucleotides 119-135 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 103-108 11786972-9 2002 Administration of c-fos antisense oligonucleotides eliminated the hyperdynamic circulation in PVS rats, but had no effect on sham-operated controls. Oligonucleotides 34-50 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 18-23 11354804-4 2001 Intrathecal injection of L-NA, nNOS antisense oligonucleotides significantly inhibited the expression of Fos-LI in the spinal cord and decreased the scores for morphine-withdrawal symptoms in morphine-withdrawal rats, but not in nNOS-S group. Oligonucleotides 46-62 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 105-108 11798865-0 2001 [Protective effect of c-fos antisense oligonucleotides on brain damage induced by glutamate]. Oligonucleotides 38-54 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 22-27 11798865-2 2001 METHODS: c-fos antisense oligonucleotides (AS ODN) was injected into the right lateral ventricles of 9 SD rats to block the c-fos gene expression in brain tissue. Oligonucleotides 25-41 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 9-14 11798865-2 2001 METHODS: c-fos antisense oligonucleotides (AS ODN) was injected into the right lateral ventricles of 9 SD rats to block the c-fos gene expression in brain tissue. Oligonucleotides 25-41 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 124-129 11798865-3 2001 c-fos sense oligonucleotides (S ODN) was used a control. Oligonucleotides 12-28 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-5 11311795-4 2001 Both the re-expression of angiotensin II subtype 1 receptor messenger RNA and restoration of pressor response to angiotensin II after baroreceptor activation were significantly blunted by bilateral application into the nucleus tractus solitarii of an antisense oligonucleotide (50 pmol) that targets against the initiation codon of c-fos messenger RNA. Oligonucleotides 261-276 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 332-337 11311795-5 2001 Control pretreatment with the corresponding sense oligonucleotide (50 pmol), or an antisense c-fos oligonucleotide that targets against a different portion of the coding sequence of the c-fos messenger RNA (50 pmol), was ineffective. Oligonucleotides 99-114 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 93-98 10377372-0 1999 An antisense oligonucleotide reverses the footshock-induced expression of fos in the rat medial prefrontal cortex and the subsequent expression of conditioned fear-induced immobility. Oligonucleotides 13-28 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 74-77 12516397-0 2000 [Potential anxiolytic role of c-fos antisense oligonucleotide in social-defeated rats]. Oligonucleotides 46-61 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 30-35 10455919-0 1999 Antisense oligonucleotides to c-fos and c-jun inhibit intimal thickening in a rat vein graft model. Oligonucleotides 10-26 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 30-35 10377372-8 1999 In other animals, an antisense oligonucleotide directed against the c-fos mRNA was injected into the infralimbic/prelimbic cortex 12 or 72 hr before the acquisition session. Oligonucleotides 31-46 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 68-73 10377372-11 1999 The antisense oligonucleotide blockade of Fos production during acquisition was associated with a significantly less fearful response during the extinction session. Oligonucleotides 14-29 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 42-45 9593045-1 1998 The fate of 15-mer phosphorothioate-modified antisense oligonucleotides to c-fos was followed after their microinjection into rat brain. Oligonucleotides 55-71 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 75-80 9822457-2 1998 Microinjection into the bilateral nucleus tractus solitarii of an antisense oligonucleotide that targets against the initiation codon of c-fos mRNA significantly potentiated the baroreceptor reflex in response to 30 minutes of sustained increase in blood pressure. Oligonucleotides 76-91 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 137-142 9822457-5 1998 Control treatment with the corresponding sense oligonucleotide, an antisense oligonucleotide that targets against a different portion of the coding sequence of the c-fos mRNA or artificial cerebrospinal fluid, on the other hand, elicited no discernible effect on either the baroreceptor reflex response or the induced expression of Fos protein in the nucleus tractus solitarii by baroreceptor activation. Oligonucleotides 47-62 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 164-169 9822457-5 1998 Control treatment with the corresponding sense oligonucleotide, an antisense oligonucleotide that targets against a different portion of the coding sequence of the c-fos mRNA or artificial cerebrospinal fluid, on the other hand, elicited no discernible effect on either the baroreceptor reflex response or the induced expression of Fos protein in the nucleus tractus solitarii by baroreceptor activation. Oligonucleotides 77-92 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 164-169 9826788-2 1998 In the present study, treatment of cultured rat embryonic basal forebrain neurons with anti-c-fos, prior to administering NGF, blocked NGF-mediated increases in ChAT activity by 67%; basal ChAT activity was not affected by the antisense oligonucleotide treatment. Oligonucleotides 237-252 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 92-97 9668442-0 1998 Cocaine-inhibited neuronal differentiation in NGF-induced PC12 cells and altered c-fos expression are reversed by C-fos antisense oligonucleotide. Oligonucleotides 130-145 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 81-86 9668442-0 1998 Cocaine-inhibited neuronal differentiation in NGF-induced PC12 cells and altered c-fos expression are reversed by C-fos antisense oligonucleotide. Oligonucleotides 130-145 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 114-119 10406025-0 1999 Antisense oligonucleotides to C-fos reduce postictal seizure susceptibility following fully kindled seizures in rats. Oligonucleotides 10-26 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 30-35 10406025-1 1999 In a previous study we demonstrated that increased FOS expression in the amygdala induced by partial kindling seizures could be attenuated by administering c-Fos specific antisense oligonucleotides. Oligonucleotides 181-197 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 51-54 10406025-1 1999 In a previous study we demonstrated that increased FOS expression in the amygdala induced by partial kindling seizures could be attenuated by administering c-Fos specific antisense oligonucleotides. Oligonucleotides 181-197 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 156-161 10406025-2 1999 In addition, we found that the administration of c-Fos antisense oligonucleotides at the beginning of the amygdala kindling process facilitated the appearance of stage V kindled seizures. Oligonucleotides 65-81 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 49-54 10406025-5 1999 However, c-Fos antisense oligonucleotides significantly reduced the susceptibility to additional ictal events during the postictal refractory period. Oligonucleotides 25-41 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 9-14 10375656-0 1999 Suppression of post-ischemic-induced fos protein expression by an antisense oligonucleotide to c-fos mRNA leads to increased tissue damage. Oligonucleotides 76-91 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 37-40 10375656-0 1999 Suppression of post-ischemic-induced fos protein expression by an antisense oligonucleotide to c-fos mRNA leads to increased tissue damage. Oligonucleotides 76-91 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 95-100 10375656-3 1999 To study the downstream effects of c-fos expression following ischemia, we suppressed the translation of c-fos by administering an antisense oligonucleotide (AO) to c-fos mRNA. Oligonucleotides 141-156 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 105-110 10375656-3 1999 To study the downstream effects of c-fos expression following ischemia, we suppressed the translation of c-fos by administering an antisense oligonucleotide (AO) to c-fos mRNA. Oligonucleotides 141-156 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 105-110 8943073-3 1996 Intrastriatal infusion of the c-fos antisense oligonucleotide profoundly decreased dialysate GABA levels in the ipsilateral substantia nigra within 60 min but did not influence the dialysate GABA levels in the globus pallidus compared with the sham and control oligonucleotide treated groups. Oligonucleotides 261-276 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 30-35 9374754-0 1997 Enhancement of spontaneous baroreflex by antisense c-fos oligonucleotide treatment in the NTS of the rat. Oligonucleotides 57-72 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 51-56 9374754-2 1997 In adult male Sprague-Dawley rats anesthetized and maintained with pentobarbital sodium, microinjection bilaterally into the caudal NTS of a 15-mer antisense oligonucleotide that targets against the initiation codon of c-fos mRNA (5"-129 to 143-3") significantly enhanced the spontaneous BRR response, as determined by transfer function analysis of SAP and heart rate signals. Oligonucleotides 158-173 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 219-224 9376532-0 1997 Neuroprotective role of c-fos antisense oligonucleotide: in vitro and in vivo studies. Oligonucleotides 40-55 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 24-29 9001250-4 1997 v-Fos-transformed cell invasion is inhibited by c-jun antisense oligonucleotides and by expression of a c-jun dominant negative mutant, TAM-67. Oligonucleotides 64-80 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 2-5 9001250-8 1997 CD44 antisense oligonucleotides reduce expression of CD44 in v-Fos- or EGF-transformed cells and inhibit invasion but not migration. Oligonucleotides 15-31 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 63-66 9555037-6 1998 The subsequent induction of PENK and PDYN mRNAs was reduced by more than 60% by the c-fos antisense oligonucleotide, while constitutive expression of three other genes (alpha-tubulin, NMDA receptor-1, and GS protein alpha-subunit) was not affected. Oligonucleotides 100-115 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 84-89 9016916-1 1996 The effect of acute and chronic administration of dopamine receptor antagonists on the expression of mRNA encoding the cellular immediate-early gene c-fos was investigated in rat brain by in situ hybridization using 35S-labelled oligonucleotide probes. Oligonucleotides 229-244 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 149-154 8943073-0 1996 Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat. Oligonucleotides 41-56 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 25-30 8943073-1 1996 Antisense c-fos oligonucleotides injected into the neostriatum of conscious rats selectively inhibited c-fos expression associated with compensatory increases in striatal c-fos mRNA levels and also with increased expression of junB and NGFI-A mRNA, probably as a result of regulatory phenomena. Oligonucleotides 16-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 10-15 8943073-1 1996 Antisense c-fos oligonucleotides injected into the neostriatum of conscious rats selectively inhibited c-fos expression associated with compensatory increases in striatal c-fos mRNA levels and also with increased expression of junB and NGFI-A mRNA, probably as a result of regulatory phenomena. Oligonucleotides 16-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 103-108 8943073-1 1996 Antisense c-fos oligonucleotides injected into the neostriatum of conscious rats selectively inhibited c-fos expression associated with compensatory increases in striatal c-fos mRNA levels and also with increased expression of junB and NGFI-A mRNA, probably as a result of regulatory phenomena. Oligonucleotides 16-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 103-108 8943073-3 1996 Intrastriatal infusion of the c-fos antisense oligonucleotide profoundly decreased dialysate GABA levels in the ipsilateral substantia nigra within 60 min but did not influence the dialysate GABA levels in the globus pallidus compared with the sham and control oligonucleotide treated groups. Oligonucleotides 46-61 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 30-35 8754788-7 1996 The stimulation of TH mRNA was mediated by the AT1 receptor subtype, resulted from an increase in its transcription, and involved activation of phospholipase C and protein kinase C. Antisense oligonucleotide for c-fos attenuated Ang II stimulation of TH mRNA in a time- and dose-dependent fashion, indicating an involvement of c-fos as a putative third messenger in Ang II stimulation of TH. Oligonucleotides 192-207 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 212-217 8949925-5 1996 This increase in Fos-LI in the barosensitive NTS neurons was appreciably reduced by bilateral microinjection into the caudal NTS of an antisense oligonucleotide (20 pmol, 20 nl) designed to target a region of the c-fos mRNA that flanks the initiation codon (5"-129 to 143-3"). Oligonucleotides 145-160 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 17-20 8949925-5 1996 This increase in Fos-LI in the barosensitive NTS neurons was appreciably reduced by bilateral microinjection into the caudal NTS of an antisense oligonucleotide (20 pmol, 20 nl) designed to target a region of the c-fos mRNA that flanks the initiation codon (5"-129 to 143-3"). Oligonucleotides 145-160 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 213-218 8754788-7 1996 The stimulation of TH mRNA was mediated by the AT1 receptor subtype, resulted from an increase in its transcription, and involved activation of phospholipase C and protein kinase C. Antisense oligonucleotide for c-fos attenuated Ang II stimulation of TH mRNA in a time- and dose-dependent fashion, indicating an involvement of c-fos as a putative third messenger in Ang II stimulation of TH. Oligonucleotides 192-207 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 327-332 8804719-3 1996 In this study, AP-1 DNA binding activity, an indicator of the functional form of the c-fos transcription factor, was examined in nuclear extracts prepared from these brain regions using an electrophoretic mobility shift assay and a labeled oligonucleotide containing the AP-1 consensus sequence. Oligonucleotides 240-255 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 85-90 8710367-3 1996 Fos binding sites were immunoselected from random sequence oligonucleotides using a pan Fos anti-serum with nuclear protein from quiescent FBRp75v-fos-transformed (FBR) and normal (208F) rat fibroblasts. Oligonucleotides 59-75 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-3 8641204-6 1996 Ang II stimulation of PAI-1 mRNA succeeded its action on c-fos mRNA and was attenuated by c-fos antisense oligonucleotide. Oligonucleotides 106-121 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 90-95 7583020-5 1995 In addition, we show by intra-striatal injection of antisense oligonucleotides directed against CREB mRNA, that CREB protein is required for c-fos induction by amphetamine. Oligonucleotides 62-78 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 141-146 8730515-7 1996 Stimulation of c-fos by v-Src in growing cells, however, coincided with formation of a complex with an oligonucleotide spanning the c-Sis-inducible element (SIE) upstream from the SRE, suggesting that the signal transduction and activator of transcription (STAT) family of transcription factors, which bind here, may function in response to the v-Src oncoprotein. Oligonucleotides 103-118 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 15-20 7608202-5 1995 An oligonucleotide representing the AP-1 recognition sequence also blocked the NFAT DNA binding activity, as did a combination of anti-Fos and anti-Jun antibodies. Oligonucleotides 3-18 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 135-138 7864828-4 1995 Gel-retardation assay indicates Fos as a component of the complex formed between the consensus oligonucleotide of the TPA (PMA, phorbol 12-myristate 13-acetate) response element (TRE) and nuclear extract prepared from butyrate-treated cells. Oligonucleotides 95-110 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 32-35 7605952-3 1995 In this study, antisense oligonucleotides complementary to c-fos mRNA were employed to interfere with the expression of Fos protein. Oligonucleotides 25-41 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 59-64 7605952-3 1995 In this study, antisense oligonucleotides complementary to c-fos mRNA were employed to interfere with the expression of Fos protein. Oligonucleotides 25-41 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 120-123 7605952-4 1995 Injections in the rat medial preoptic area of c-fos antisense, but not of sense, oligonucleotides blocked the expression of Fos protein detected immunocytochemically. Oligonucleotides 81-97 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 46-51 7804603-0 1994 c-fos antisense oligonucleotide specifically attenuates haloperidol-induced increases in neurotensin/neuromedin N mRNA expression in rat dorsal striatum. Oligonucleotides 16-31 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-5 8087422-3 1994 Previous work in our laboratory demonstrated by gel shift analysis that Fos and non-Fos-containing complexes formed with oligonucleotides containing this element. Oligonucleotides 121-137 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 72-75 8087422-3 1994 Previous work in our laboratory demonstrated by gel shift analysis that Fos and non-Fos-containing complexes formed with oligonucleotides containing this element. Oligonucleotides 121-137 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 84-87 8298093-1 1993 Sodium pentobarbital anaesthetized rats were injected ipsilaterally with an antisense oligonucleotide to c-fos and contralaterally with a sense of oligonucleotide to c-fos in the striatum. Oligonucleotides 86-101 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 105-110 8184987-2 1994 In six male Wistar-Kyoto rats (WKY), unilateral injection of an antisense oligonucleotide to c-fos mRNA suppressed the expression of Fos-like immunoreactivity in neurons in the RVM in response to inhibition of depressor neurons in the caudal ventrolateral medulla (CVLM). Oligonucleotides 74-89 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 93-98 8184987-2 1994 In six male Wistar-Kyoto rats (WKY), unilateral injection of an antisense oligonucleotide to c-fos mRNA suppressed the expression of Fos-like immunoreactivity in neurons in the RVM in response to inhibition of depressor neurons in the caudal ventrolateral medulla (CVLM). Oligonucleotides 74-89 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 133-136 8184987-5 1994 These studies demonstrate that expression of c-fos in the RVM can be blocked in vivo by treatment with an antisense oligonucleotide, and that basal and stimulated expression of the c-fos gene is important in the central control of arterial blood pressure. Oligonucleotides 116-131 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 45-50 8298090-0 1993 Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine. Oligonucleotides 10-25 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 29-34 7510676-11 1994 One consequence of the activation of STAT91 in the nucleus is the appearance of GH-stimulated DNA binding activity, as assessed by gel-mobility shift assay using an oligonucleotide containing a c-sis-inducible element from the c-fos promoter. Oligonucleotides 165-180 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 227-232 8298093-1 1993 Sodium pentobarbital anaesthetized rats were injected ipsilaterally with an antisense oligonucleotide to c-fos and contralaterally with a sense of oligonucleotide to c-fos in the striatum. Oligonucleotides 147-162 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 166-171 8298093-4 1993 The antisense oligonucleotide also strongly inhibited the amphetamine-induced expression of c-Fos and Jun B in striatal neurones. Oligonucleotides 14-29 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 92-97 1549354-2 1992 This C-kinase-induced expression of c-fos was prevented by in vivo competition using co-injection of oligonucleotides corresponding to the sequence of either the serum response element (SRE) or the fos AP-1 binding sequence (FAP) adjacent to SRE. Oligonucleotides 101-117 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 36-41 1320720-1 1992 Messenger RNA encoding the immediate early genes (IEGs) c-fos and NGFI-A was localized by in situ hybridization of specific 35S-labelled oligonucleotides to detect activated neurones in the medulla oblongata following unilateral electrical stimulation of the vagus (nX) and aortic depressor nerve (ADN), and following mechanical stimulation of the left carotid sinus (CS). Oligonucleotides 137-153 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 56-61 1737937-3 1992 The inducible nuclear proteins binding to this site have the characteristics of AP-1, as judged by their kinetics of induction, the ability to compete and be competed efficiently by a metallothionein AP-1 site oligonucleotide, and their reaction with antibodies to Fos and Jun proteins. Oligonucleotides 210-225 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 265-268 8476611-1 1993 By using spinal cord neurons cultured in chemically defined medium, a double labeling procedure, and blockage with antisense oligonucleotides, we show that induction of c-fos and the subsequent transactivation of the prodynorphin gene are coupled events, triggered by serotonin1A receptor agonists. Oligonucleotides 125-141 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 169-174 1549354-4 1992 In contrast, the induction of c-fos by serum or by casein kinase II microinjection, which is also inhibited by injection of SRE oligonucleotides, is only delayed and then markedly prolonged by injecting TRE/FAP sequence, demonstrating that the FAP site plays a prominent role in vivo in the down-regulation of the endogenous c-fos gene expression. Oligonucleotides 128-144 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 30-35 2110508-3 1990 When coinjected with an SRE oligonucleotide, it induced c-fos expression in quiescent cells, whereas injection of SRE sequence alone failed to do so. Oligonucleotides 28-43 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 56-61 1915270-2 1991 The induction of c-fos by CKII is inhibited by coinjection of oligonucleotides corresponding to the sequence of the serum response element (SRE) present in the c-fos promoter, indicating that competitive displacement of positive factors from the endogenous c-fos SRE prevents c-fos induction by CKII. Oligonucleotides 62-78 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 17-22 1915270-2 1991 The induction of c-fos by CKII is inhibited by coinjection of oligonucleotides corresponding to the sequence of the serum response element (SRE) present in the c-fos promoter, indicating that competitive displacement of positive factors from the endogenous c-fos SRE prevents c-fos induction by CKII. Oligonucleotides 62-78 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 160-165 1915270-2 1991 The induction of c-fos by CKII is inhibited by coinjection of oligonucleotides corresponding to the sequence of the serum response element (SRE) present in the c-fos promoter, indicating that competitive displacement of positive factors from the endogenous c-fos SRE prevents c-fos induction by CKII. Oligonucleotides 62-78 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 160-165 1915270-2 1991 The induction of c-fos by CKII is inhibited by coinjection of oligonucleotides corresponding to the sequence of the serum response element (SRE) present in the c-fos promoter, indicating that competitive displacement of positive factors from the endogenous c-fos SRE prevents c-fos induction by CKII. Oligonucleotides 62-78 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 160-165 2104799-3 1990 This c-fos expression can be specifically suppressed by coinjection of a double-stranded oligonucleotide which corresponds to the serum response element (SRE) present in the c-fos promoter, implying that ras utilizes a pathway which activates the binding of serum response factor(s) (SRF) to SRE to induce c-fos transcription. Oligonucleotides 89-104 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 5-10 2104799-3 1990 This c-fos expression can be specifically suppressed by coinjection of a double-stranded oligonucleotide which corresponds to the serum response element (SRE) present in the c-fos promoter, implying that ras utilizes a pathway which activates the binding of serum response factor(s) (SRF) to SRE to induce c-fos transcription. Oligonucleotides 89-104 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 174-179 2104799-3 1990 This c-fos expression can be specifically suppressed by coinjection of a double-stranded oligonucleotide which corresponds to the serum response element (SRE) present in the c-fos promoter, implying that ras utilizes a pathway which activates the binding of serum response factor(s) (SRF) to SRE to induce c-fos transcription. Oligonucleotides 89-104 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 174-179 31119435-6 2019 The SMGI, astrocyte and neuron activity were affected after the astrocytotoxin L-A-aminohexanedioic acid (L-AA) and c-fos antisense oligonucleotide (ASO) injections. Oligonucleotides 132-147 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 116-121 24316406-6 2014 Intrathecal administration of Homer 1b/c antisense oligonucleotides not only markedly reduced the expression of Homer 1b/c protein, but also attenuated CFA-induced inflammation, spinal CREB phosphorylation, and Fos expression. Oligonucleotides 51-67 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 211-214 2108404-5 1990 Nonetheless, upon activating the pp60v-src protein kinase there is a marked and rapid increase in the ability of ts LA 29 Rat-1 nuclear extracts to retard the gel migration of oligonucleotides containing the AP-1 binding site, indicating that pp60v-src activity leads to an enhanced functioning of Fos and Jun related proteins that may, in turn, affect their transcriptional activation. Oligonucleotides 176-192 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 298-301 26646512-5 2017 Interestingly, this increase was associated with memory durability, since blocking c-Fos expression using specific antisense oligonucleotides (ASO) impaired long-lasting retention 7 days after training without affecting memory expression 2 days after training. Oligonucleotides 125-141 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 83-88