PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1534660-5 1992 Consistent with these observations, treatment of rats with loratadine caused a dose-dependent increase in the rate of two reactions that are catalyzed predominantly by 2B1/2, namely testosterone 16 beta-hydroxylation and 7-pentoxyresorufin O-dealkylation. Testosterone 182-194 UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus 168-173 1520294-6 1992 In addition, 7,7,7-triphenylheptyl-UDP (0.25-0.50 mM) almost inhibited glucuronidation of 1-naphthol and testosterone catalyzed by the recombinant rat liver UGT-2B1 and human liver UGT-1A1, whose cDNA has been expressed in V79 cells. Testosterone 105-117 UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus 157-164 10100302-4 1999 RESULTS: Treatment with 10(-5) M testosterone increased the mRNA levels of UGT 2B1 by 29% and UGT2B3 by 32%. Testosterone 33-45 UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus 75-82 2113533-1 1990 A lambda clone containing the entire gene and flanking sequences for a form of UDP-glucuronosyltransferase (UDPGTr-2) that glucuronidates testosterone and the foreign compounds, 4-hydroxybiphenyl and chloramphenicol, has been isolated from a rat liver genomic library. Testosterone 138-150 UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus 108-116 3110162-8 1987 Whereas both enzymes glucuronidated the endogenous steroids testosterone, dihydrotestosterone, and beta-estradiol, only UDPGTr-2 was active towards the foreign chemical substrates, chloramphenicol, 4-hydroxybiphenyl, and 4-methylumbelliferone. Testosterone 60-72 UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus 120-128