PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7964297-9	1994	Although ET-1 did not affect DNA synthesis stimulated by either EGF or IGF-I, it dose-dependently inhibited TSH-induced iodide uptake and also inhibited iodide uptake stimulated by forskolin and 8-bromo-cAMP.	8-Bromo Cyclic Adenosine Monophosphate	195-207	endothelin 1	Homo sapiens	9-13	
1377954-5	1992	The decrease in the t-PA:Ag release induced by endothelin-1 occurred in the presence or absence of 8-bromo cyclic AMP, which is an active congener of cyclic AMP; 3-isobutyl-1-methylxanthine, which is an inhibitor of phosphodiesterase; and forskolin, which is a stimulator of adenylate cyclase.	8-Bromo Cyclic Adenosine Monophosphate	99-117	endothelin 1	Homo sapiens	47-59	
15513924-2	2005	In this study we have presented evidence that treatment of human mesangial cells (HMC) with endothelin 1 (ET-1) and stimulation of adenylate cyclase with either forskolin or with the cAMP analog 8-Br-cAMP activated the GTP loading of Cdc42.	8-Bromo Cyclic Adenosine Monophosphate	195-204	endothelin 1	Homo sapiens	92-104	
11028503-9	2000	Endothelin-1 also inhibited apoptosis induced by a membrane-permeable cAMP analogue (8-Br-cAMP), which bypassed Gi.	8-Bromo Cyclic Adenosine Monophosphate	85-94	endothelin 1	Homo sapiens	0-12	
15115660-11	2004	The synergistic action of ET-1 with 8-bromo cAMP to enhance glucose transport was inhibited by GF109203X, a selective protein kinase C (PKC) inhibitor, and was mimicked by 4beta-phorbol 12beta-myristate 13alpha-acetate (PMA), a PKC activator.	8-Bromo Cyclic Adenosine Monophosphate	36-48	endothelin 1	Homo sapiens	26-30