PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11340082-7 2001 Supporting these data, the cells examined expressed PTPzeta, a receptor-type protein-tyrosine phosphatase that exhibits high affinity to both midkine and pleiotrophin and harbors chondroitin sulfate chains. Chondroitin Sulfates 179-198 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 52-59 16513268-1 2006 Ptprz is a receptor-type protein tyrosine phosphatase predominantly expressed in the brain as a chondroitin sulfate proteoglycan. Chondroitin Sulfates 96-115 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 0-5 14757526-1 2004 Protein tyrosine phosphatase zeta (PTPzeta)/RPTPbeta is a chondroitin sulfate proteoglycan predominantly expressed in the brain. Chondroitin Sulfates 58-77 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 0-43 14757526-1 2004 Protein tyrosine phosphatase zeta (PTPzeta)/RPTPbeta is a chondroitin sulfate proteoglycan predominantly expressed in the brain. Chondroitin Sulfates 58-77 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 44-52 12917413-1 2003 Brain-specific chondroitin sulfate (CS) proteoglycan (PG) DSD-1-PG/6B4-PG/phosphacan isolated from neonatal mouse brains exhibits neurite outgrowth-promoting activity toward embryonic rat and mouse hippocampal neurons in vitro through the so-called DSD-1 epitope embedded in its glycosaminoglycan side chains. Chondroitin Sulfates 15-34 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 58-66 12917413-1 2003 Brain-specific chondroitin sulfate (CS) proteoglycan (PG) DSD-1-PG/6B4-PG/phosphacan isolated from neonatal mouse brains exhibits neurite outgrowth-promoting activity toward embryonic rat and mouse hippocampal neurons in vitro through the so-called DSD-1 epitope embedded in its glycosaminoglycan side chains. Chondroitin Sulfates 36-38 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 58-66 9655611-1 1998 PTPzeta/RPTPbeta is a receptor-like protein tyrosine phosphatase expressed as a chondroitin sulfate proteoglycan. Chondroitin Sulfates 80-99 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 0-7 9600379-1 1998 DSD-1-PG is a chondroitin sulfate proteoglycan with neurite-outgrowth promoting properties expressed during development and upon lesion of neural tissues which has been defined with the specific monoclonal antibody 473HD. Chondroitin Sulfates 14-33 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 0-8 9655611-1 1998 PTPzeta/RPTPbeta is a receptor-like protein tyrosine phosphatase expressed as a chondroitin sulfate proteoglycan. Chondroitin Sulfates 80-99 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 8-16 7519189-3 1994 We report here that the monoclonal antibody 473HD, which binds to the surface of early differentiation stages of murine astrocytes and oligodendrocytes, reacts with the chondroitin sulfate/dermatan sulfate hybrid epitope DSD-1 expressed on a central nervous system chondroitin sulfate proteoglycan designated DSD-1-PG. Chondroitin Sulfates 169-188 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 309-317 9452446-1 1998 A mouse brain chondroitin sulfate (CS) proteoglycan, DSD-1-PG, bears the DSD-1 epitope and has neurite outgrowth promoting properties. Chondroitin Sulfates 14-33 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 53-61 9452446-1 1998 A mouse brain chondroitin sulfate (CS) proteoglycan, DSD-1-PG, bears the DSD-1 epitope and has neurite outgrowth promoting properties. Chondroitin Sulfates 35-37 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 53-61 9452446-2 1998 Shark cartilage CS-C inhibits the interactions between the DSD-1-specific monoclonal antibody 473HD and the CS chains of the DSD-1-PG, which is expressed on the mouse glial cells (Faissner, A., Clement, A., Lochter, A., Streit, A., Mandl, C., and Schachner, M. (1994) J. Chondroitin Sulfates 16-18 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 125-133 7519189-3 1994 We report here that the monoclonal antibody 473HD, which binds to the surface of early differentiation stages of murine astrocytes and oligodendrocytes, reacts with the chondroitin sulfate/dermatan sulfate hybrid epitope DSD-1 expressed on a central nervous system chondroitin sulfate proteoglycan designated DSD-1-PG. Chondroitin Sulfates 265-284 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 309-317 27445335-0 2016 Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. Chondroitin Sulfates 8-27 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 67-111 34169071-2 2021 The chondroitin sulfate proteoglycan (CSPG) DSD-1-PG is an isoform of receptor protein tyrosine phosphatase-beta/zeta (RPTPbeta/zeta), a trans-membrane receptor expressed by NSPCs. Chondroitin Sulfates 4-23 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 44-52 34169071-2 2021 The chondroitin sulfate proteoglycan (CSPG) DSD-1-PG is an isoform of receptor protein tyrosine phosphatase-beta/zeta (RPTPbeta/zeta), a trans-membrane receptor expressed by NSPCs. Chondroitin Sulfates 4-23 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 119-127 27445335-3 2016 The extracellular CS moiety of PTPRZ is required for high-affinity binding to inhibitory ligands, such as pleiotrophin (PTN), midkine, and interleukin-34; however, its functional significance in regulating PTPRZ activity remains obscure. Chondroitin Sulfates 18-20 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 206-211 27445335-4 2016 We herein found that protein expression of CS-modified PTPRZ-A began earlier, peaking at approximately postnatal days 5-10 (P5-P10), and then that of PTN peaked at P10 at the developmental stage corresponding to myelination onset in the mouse brain. Chondroitin Sulfates 43-45 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 55-60 27445335-8 2016 These results indicate that the negatively charged CS moiety prevents PTPRZ from spontaneously clustering and that the positively charged ligand PTN induces PTPRZ clustering, potentially by neutralizing electrostatic repulsion between CS chains. Chondroitin Sulfates 235-237 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 157-162 27445335-9 2016 Taken altogether, these data indicate that PTN-PTPRZ-A signaling controls the timing of oligodendrocyte precursor cell differentiation in vivo, in which the CS moiety of PTPRZ receptors maintains them in a monomeric active state until its ligand binding. Chondroitin Sulfates 157-159 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 47-52 27445335-9 2016 Taken altogether, these data indicate that PTN-PTPRZ-A signaling controls the timing of oligodendrocyte precursor cell differentiation in vivo, in which the CS moiety of PTPRZ receptors maintains them in a monomeric active state until its ligand binding. Chondroitin Sulfates 157-159 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 170-175 27445335-0 2016 Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. Chondroitin Sulfates 8-27 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 113-118 27445335-0 2016 Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. Chondroitin Sulfates 8-27 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 143-148 27445335-0 2016 Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. Chondroitin Sulfates 29-31 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 67-111 27445335-0 2016 Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. Chondroitin Sulfates 29-31 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 113-118 27445335-0 2016 Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. Chondroitin Sulfates 29-31 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 143-148 27445335-3 2016 The extracellular CS moiety of PTPRZ is required for high-affinity binding to inhibitory ligands, such as pleiotrophin (PTN), midkine, and interleukin-34; however, its functional significance in regulating PTPRZ activity remains obscure. Chondroitin Sulfates 18-20 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 31-36 23744080-4 2013 By IL-34 affinity chromatography of solubilized mouse brain membrane followed by mass spectrometric analysis, we identified receptor-type protein-tyrosine phosphatase zeta (PTP-zeta), a cell surface chondroitin sulfate (CS) proteoglycan, as a novel IL-34 receptor. Chondroitin Sulfates 199-218 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 173-181 23744080-4 2013 By IL-34 affinity chromatography of solubilized mouse brain membrane followed by mass spectrometric analysis, we identified receptor-type protein-tyrosine phosphatase zeta (PTP-zeta), a cell surface chondroitin sulfate (CS) proteoglycan, as a novel IL-34 receptor. Chondroitin Sulfates 220-222 protein tyrosine phosphatase, receptor type Z, polypeptide 1 Mus musculus 173-181