PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8964835-2 1996 We measured the effects of PGF2 alpha and fluprostenol, a selective PGF2 alpha receptor (FP receptor) agonist, on phospholipase C(PLC) activation, on changes in the intracellular free calcium concentration ([Ca2+]i), and on protein tyrosine phosphorylation. fluprostenol 42-54 heparan sulfate proteoglycan 2 Homo sapiens 130-133 8964835-3 1996 PGF2 alpha and fluprostenol activated PLC (determined by measuring the formation of inositol phosphates) and increased [Ca2+]i in a concentration-dependent manner. fluprostenol 15-27 heparan sulfate proteoglycan 2 Homo sapiens 38-41 8964835-4 1996 The apparent affinity of the FP receptor for fluprostenol was higher than that for PGF2 alpha when measuring PLC activation, but the receptor displayed similar affinities for both agonists when measuring increases in [Ca2+]i. fluprostenol 45-57 heparan sulfate proteoglycan 2 Homo sapiens 109-112 8964835-9 1996 These data suggest that fluprostenol and oxytocin activate PLC-beta rather than PLC-gamma isoforms. fluprostenol 24-36 heparan sulfate proteoglycan 2 Homo sapiens 59-62 8964835-9 1996 These data suggest that fluprostenol and oxytocin activate PLC-beta rather than PLC-gamma isoforms. fluprostenol 24-36 heparan sulfate proteoglycan 2 Homo sapiens 80-83