PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34106748-12 2021 4-HPR (also known as fenretinide) is an inhibitor of DES1 and it exhibits antitumor activity and suppresses cell-cell fusion and viral infection. Fenretinide 0-5 delta 4-desaturase, sphingolipid 1 Homo sapiens 53-57 34106748-3 2021 N-(4-hydroxyphenyl) retinamide (4-HPR), an inhibitor of dihydroceramide Delta4-desaturase 1 (DES1), suppressed cell-cell fusion, and viral infection. Fenretinide 0-30 delta 4-desaturase, sphingolipid 1 Homo sapiens 93-97 34106748-3 2021 N-(4-hydroxyphenyl) retinamide (4-HPR), an inhibitor of dihydroceramide Delta4-desaturase 1 (DES1), suppressed cell-cell fusion, and viral infection. Fenretinide 32-37 delta 4-desaturase, sphingolipid 1 Homo sapiens 93-97 34106748-12 2021 4-HPR (also known as fenretinide) is an inhibitor of DES1 and it exhibits antitumor activity and suppresses cell-cell fusion and viral infection. Fenretinide 21-32 delta 4-desaturase, sphingolipid 1 Homo sapiens 53-57 31631013-4 2019 Inhibition of DEGS1 in hematopoietic stem and progenitor cells during the transition from quiescence to cellular activation with N-(4-hydroxyphenyl) retinamide activates coordinated stress pathways that coalesce on endoplasmic reticulum stress and autophagy programs to maintain immunophenotypic and functional HSCs. Fenretinide 129-159 delta 4-desaturase, sphingolipid 1 Homo sapiens 14-19 29500274-8 2018 Complementary experiments in these animal models using the DES1 inhibitor fenretinide show more modest effects on cone recovery. Fenretinide 74-85 delta 4-desaturase, sphingolipid 1 Homo sapiens 59-63 28448568-0 2017 Inhibitory effects of fenretinide metabolites N-[4-methoxyphenyl]retinamide (MPR) and 4-oxo-N-(4-hydroxyphenyl)retinamide (3-keto-HPR) on fenretinide molecular targets beta-carotene oxygenase 1, stearoyl-CoA desaturase 1 and dihydroceramide Delta4-desaturase 1. Fenretinide 22-33 delta 4-desaturase, sphingolipid 1 Homo sapiens 247-260 26934645-3 2016 These effects are recapitulated by the dihydroceramide desaturase (Des1) inhibitor, fenretinide. Fenretinide 84-95 delta 4-desaturase, sphingolipid 1 Homo sapiens 67-71