PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33380244-4	2021	Intraperitoneally administered 4-HPR particularly at dose of 100 mg/kg obviously alleviated UC symptoms and restrained the mRNA expression of colonic IL-1beta, IL-6, and TNF-alpha in dextran sulfate sodium (DSS)-induced mice.	Fenretinide	31-36	interleukin 6	Mus musculus	160-164	
23139430-4	2013	Moreover, fenretinide attenuated interleukin (IL)-1beta, IL-6, and cyclooxygenase-2 mRNA expression induced by A. actinomycetemcomitans.	Fenretinide	10-21	interleukin 6	Mus musculus	57-61	
23139430-5	2013	Fenretinide also decreased IL-1beta, IL-6, and prostaglandin E2 proinflammatory cytokine levels in Raw 264.7 cells induced by A. actinomycetemcomitans.	Fenretinide	0-11	interleukin 6	Mus musculus	37-41	
24069363-5	2013	Indeed, our results demonstrate that 4HPR inhibited the excessive production of inflammatory mediators, including TNF, IL-6, CCL2 and CCL-5 in LPS-stimulated FXR1-KO macrophages, by selectively inhibiting phosphorylation of ERK1/2, which is naturally more phosphorylated in FXR1-KO cells.	Fenretinide	37-41	interleukin 6	Mus musculus	119-123