PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34427649-1 2022 BACKGROUND: The first-in-class treatment PF-06480605 targets the tumor necrosis factor-like ligand 1A (TL1A) molecule in humans. pf-06480605 41-52 TNF superfamily member 15 Homo sapiens 65-101 34427649-1 2022 BACKGROUND: The first-in-class treatment PF-06480605 targets the tumor necrosis factor-like ligand 1A (TL1A) molecule in humans. pf-06480605 41-52 TNF superfamily member 15 Homo sapiens 103-107 34427649-8 2022 CONCLUSIONS: The ability of PF-06480605 to engage and inhibit colonic TL1A, targeting inflammatory T cell and fibrosis pathways, provides the first-in-human mechanistic data to guide anti-TL1A therapy for the treatment of IBD. pf-06480605 28-39 TNF superfamily member 15 Homo sapiens 70-74 34427649-8 2022 CONCLUSIONS: The ability of PF-06480605 to engage and inhibit colonic TL1A, targeting inflammatory T cell and fibrosis pathways, provides the first-in-human mechanistic data to guide anti-TL1A therapy for the treatment of IBD. pf-06480605 28-39 TNF superfamily member 15 Homo sapiens 188-192