PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6701446-0	1984	Effect of long-term penicillamine therapy on erythrocyte CuZn superoxide dismutase activity.	Penicillamine	20-33	superoxide dismutase 1	Homo sapiens	57-82	
6701446-1	1984	The effect of long-term penicillamine therapy on erythrocyte CuZn superoxide dismutase activity was investigated.	Penicillamine	24-37	superoxide dismutase 1	Homo sapiens	61-86	
6701446-3	1984	Seven of the 11 penicillamine-treated patients had CuZn superoxide dismutase activities below the reference interval of the parameter.	Penicillamine	16-29	superoxide dismutase 1	Homo sapiens	51-76	
6701446-7	1984	Erythrocyte CuZn superoxide dismutase is probably a suitable parameter for monitoring intracellular copper availability during penicillamine therapy.	Penicillamine	127-140	superoxide dismutase 1	Homo sapiens	12-37	
9581011-9	1998	Another drug, penicillamine, that protects cellular membranes against toxic oxygen in vitro, is presumed to act as an antirheumatic via the SOD mimetic activity of its copper complex.	Penicillamine	14-27	superoxide dismutase 1	Homo sapiens	140-143	
11958955-6	2002	Copper chelators, diethyldithiocarbamate and penicillamine, also inhibited the Cu,Zn-SOD/H(2)O(2) system-induced alpha-synuclein aggregation.	Penicillamine	45-58	superoxide dismutase 1	Homo sapiens	85-88	
33352220-3	2021	In this study, we found, interestingly and unexpectedly, that superoxide dismutase (SOD) can significantly shorten the delay of TCHQ autooxidation by penicillamine, but not by ascorbate; SOD can also markedly increase the yields of the oxidized form of penicillamine.	Penicillamine	150-163	superoxide dismutase 1	Homo sapiens	62-82	
33352220-3	2021	In this study, we found, interestingly and unexpectedly, that superoxide dismutase (SOD) can significantly shorten the delay of TCHQ autooxidation by penicillamine, but not by ascorbate; SOD can also markedly increase the yields of the oxidized form of penicillamine.	Penicillamine	150-163	superoxide dismutase 1	Homo sapiens	84-87	
33352220-3	2021	In this study, we found, interestingly and unexpectedly, that superoxide dismutase (SOD) can significantly shorten the delay of TCHQ autooxidation by penicillamine, but not by ascorbate; SOD can also markedly increase the yields of the oxidized form of penicillamine.	Penicillamine	150-163	superoxide dismutase 1	Homo sapiens	187-190	
33352220-3	2021	In this study, we found, interestingly and unexpectedly, that superoxide dismutase (SOD) can significantly shorten the delay of TCHQ autooxidation by penicillamine, but not by ascorbate; SOD can also markedly increase the yields of the oxidized form of penicillamine.	Penicillamine	253-266	superoxide dismutase 1	Homo sapiens	62-82	
33352220-3	2021	In this study, we found, interestingly and unexpectedly, that superoxide dismutase (SOD) can significantly shorten the delay of TCHQ autooxidation by penicillamine, but not by ascorbate; SOD can also markedly increase the yields of the oxidized form of penicillamine.	Penicillamine	253-266	superoxide dismutase 1	Homo sapiens	84-87	
33352220-3	2021	In this study, we found, interestingly and unexpectedly, that superoxide dismutase (SOD) can significantly shorten the delay of TCHQ autooxidation by penicillamine, but not by ascorbate; SOD can also markedly increase the yields of the oxidized form of penicillamine.	Penicillamine	253-266	superoxide dismutase 1	Homo sapiens	187-190	
9240414-4	1997	To test this hypothesis in vivo, we administered the copper chelator d-penicillamine to a transgenic mouse model of familial amyotrophic lateral sclerosis overexpressing a mutated form of human SOD1.	Penicillamine	69-84	superoxide dismutase 1	Homo sapiens	194-198