PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14644129-3	2003	By using in vitro cell invasion assay system, we evaluated the effects of amiloride and urinary trypsin inhibitor (UTI), which inhibit uPA and plasmin, respectively, on invasion by both cell lines.	Amiloride	74-83	plasminogen	Homo sapiens	143-150	
14644129-5	2003	Amiloride and UTI significantly inhibited plasmin formation and the invasion of both cell lines (p<0.001).	Amiloride	0-9	plasminogen	Homo sapiens	42-49	
14644129-7	2003	Thus, inhibitors of uPA and plasmin, such as amiloride and UTI, respectively, could be useful therapeutic tools with which to treat urothelial cancer.	Amiloride	45-54	plasminogen	Homo sapiens	28-35	
33070369-4	2020	We performed comparative studies in a puromycin aminonucleoside (PAN) nephropathy rat model treated with amiloride, an inhibitor of plasminogen activation, and measured changes in plasmin (ogen) uria.	Amiloride	105-114	plasminogen	Homo sapiens	132-139	
1652031-7	1991	However, urokinase and plasmin (both serine proteases found in mammalian urine) were found to cause an irreversible loss of amiloride-sensitive current, a variable change in the leak current as well as the appearance of a third conductance which was unstable in the apical membrane and appears to partition between the apical membrane and the mucosal solution.	Amiloride	124-133	plasminogen	Homo sapiens	23-30	
3106085-1	1987	The diuretic drug amiloride, an inhibitor of Na+ uptake, competitively inhibits the catalytic activity of the urokinase-type plasminogen activator (u-PA), with a Ki of 7 X 10(-6) M. Generation of plasmin, cleavage of peptide substrates, and interaction of u-PA with a specific macromolecular proteinase inhibitor are all prevented in the presence of the drug.	Amiloride	18-27	plasminogen	Homo sapiens	125-132	
27214087-10	2016	Urine total plasminogen and active plasmin were reduced after amiloride in diabetic nephropathy.	Amiloride	62-71	plasminogen	Homo sapiens	12-19	
27214087-11	2016	CONCLUSION: Amiloride increased renal Na excretion, reduced blood pressure, albuminuria, and total and active plasmin in urine.	Amiloride	12-21	plasminogen	Homo sapiens	110-117	
25482671-6	2015	Urine from these patients activates, plasmin-dependently, amiloride-sensitive inward current in vitro.	Amiloride	58-67	plasminogen	Homo sapiens	37-44	
23216619-11	2013	In this study, it is shown that human lymphocytes may be used to uncover the effect of urine plasmin on amiloride- and aprotinin-sensitive inward currents.	Amiloride	104-113	plasminogen	Homo sapiens	93-100