PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7543425-0 1995 Insulin-activated amiloride-blockable nonselective cation and Na+ channels in the fetal distal lung epithelium. Amiloride 18-27 insulin Homo sapiens 0-7 9612225-4 1998 We have used a noninvasive pulse protocol of blocker-induced noise analysis to determine changes in single-channel current (iNa), channel open probability (Po), and functional channel density (NT) of amiloride-sensitive ENaCs at various time points following treatment with insulin for 3 h of unstimulated control and aldosterone-pretreated A6 epithelia. Amiloride 200-209 insulin Homo sapiens 274-281 9575821-1 1998 Insulin stimulates amiloride-sensitive sodium transport in models of the distal nephron. Amiloride 19-28 insulin Homo sapiens 0-7 9094251-5 1997 Incubating the apical side of the epithelium with either amiloride or Na+-free solutions also reduced or abolished the increase in the initial rate of [3H]ouabain binding caused by insulin. Amiloride 57-66 insulin Homo sapiens 181-188 27406671-4 1996 Activation of the antiporter protein by insulin can stimulate glycolysis by an increase in intracellular pH, an effect which is prevented by amiloride. Amiloride 141-150 insulin Homo sapiens 40-47 8897813-1 1996 The individual effects of aldosterone and insulin on amiloride-sensitive Na+ transport in model renal epithelia have been well characterized. Amiloride 53-62 insulin Homo sapiens 42-49 7013841-4 1981 Both the increase in intracellular pH induced by insulin and the associated increase in intracellular Na+ produced by this hormone in the presence of ouabain are blocked by amiloride. Amiloride 173-182 insulin Homo sapiens 49-56 27405553-4 1995 Stimulation of ferricyanide reduction by insulin and somatotrophin may be also the result of Na(+)/H(+) antiport activation which may be prevented by amiloride. Amiloride 150-159 insulin Homo sapiens 41-48 7957545-6 1994 The rates of glucose production and utilization were also similar, whereas the so-called insulin sensitivity index at the lower insulin concentration was significantly reduced (by about 15%) after amiloride. Amiloride 197-206 insulin Homo sapiens 89-96 7957545-6 1994 The rates of glucose production and utilization were also similar, whereas the so-called insulin sensitivity index at the lower insulin concentration was significantly reduced (by about 15%) after amiloride. Amiloride 197-206 insulin Homo sapiens 128-135 7957545-7 1994 Moreover, amiloride produced significantly higher fasting insulin and C-peptide concentrations, whereas fasting glucose and NEFA concentrations were unaltered. Amiloride 10-19 insulin Homo sapiens 58-65 7957545-7 1994 Moreover, amiloride produced significantly higher fasting insulin and C-peptide concentrations, whereas fasting glucose and NEFA concentrations were unaltered. Amiloride 10-19 insulin Homo sapiens 70-79 7957545-8 1994 In conclusion, these data suggest that short-term amiloride slightly impairs insulin sensitivity with respect to glucose uptake. Amiloride 50-59 insulin Homo sapiens 77-84 8303861-0 1993 [The connection between insulin-dependent biosynthesis of cell membrane signal ATP with amiloride-sensitive Na+/H+-metabolism in human erythrocytes]. Amiloride 88-97 insulin Homo sapiens 24-31 1329533-7 1992 These results indicate that insulin increases Na absorption in the distal nephron by increasing the open probability of the amiloride-blockable Na channel. Amiloride 124-133 insulin Homo sapiens 28-35 2645305-5 1989 On the other hand, the induction by insulin is sensitive to amiloride, whereas that by arsenite is not. Amiloride 60-69 insulin Homo sapiens 36-43 2579572-5 1985 This insulin-induced recovery was abolished by 1 mM amiloride, a Na-H exchange inhibitor. Amiloride 52-61 insulin Homo sapiens 5-12 7957545-0 1994 Insulin concentrations and insulin sensitivity after short-term amiloride in healthy subjects. Amiloride 64-73 insulin Homo sapiens 0-7 7957545-0 1994 Insulin concentrations and insulin sensitivity after short-term amiloride in healthy subjects. Amiloride 64-73 insulin Homo sapiens 27-34 7957545-1 1994 We have evaluated the short-term effects of amiloride on insulin action in vivo, since amiloride is known to impair insulin action in vitro. Amiloride 44-53 insulin Homo sapiens 57-64 7957545-1 1994 We have evaluated the short-term effects of amiloride on insulin action in vivo, since amiloride is known to impair insulin action in vitro. Amiloride 87-96 insulin Homo sapiens 116-123 1627180-4 1992 Insulin-stimulated synthesis of the plasma membrane "signal" ATP in an amount of 1-10 nM is potentized by ionophores carbonyl cyanide p-trifluorometoxyphenylhydrazone and monensin and inhibited by amiloride and ouabain. Amiloride 197-206 insulin Homo sapiens 0-7 7013841-7 1981 Thus, the mechanism stimulated by insulin is not a Na+-CO3(2-) cotransport system, but is either an Na:H exchange or a Na+-OH- cotransport system which can be inhibited by amiloride. Amiloride 172-181 insulin Homo sapiens 34-41 12225981-0 2002 Amiloride-sensitive sodium current in everted Ambystoma initial collecting tubule: short-term insulin effects. Amiloride 0-9 insulin Homo sapiens 94-101 4574908-0 1973 The importance of the guanidine group in the insulin-stimulatory effect of amiloride hydrochloride. Amiloride 75-98 insulin Homo sapiens 45-52 24603133-0 2014 PPARgamma-induced stimulation of amiloride-sensitive sodium current in renal collecting duct principal cells is serum and insulin dependent. Amiloride 33-42 insulin Homo sapiens 122-129 21106690-3 2011 In fungiform and vallate TRCs that exhibit functional ENaC currents (e.g., amiloride-sensitive Na(+) influx), insulin (5-20 nM) caused a significant increase in Na(+) influx at -80 mV (EC(50) = 7.53 nM). Amiloride 75-84 insulin Homo sapiens 110-117 21106690-4 2011 The insulin-enhanced currents were inhibited by amiloride (30 muM). Amiloride 48-57 insulin Homo sapiens 4-11 21106690-9 2011 Interestingly, these differences between groups were abolished when amiloride (100 muM) was added into NaCl solutions, suggesting that insulin was regulating ENaC. Amiloride 68-77 insulin Homo sapiens 135-142 20237237-6 2010 COMMD1 abolished insulin-stimulated amiloride-sensitive current and attenuated the stimulation of current by activated serum and glucocorticoid-regulated kinase (SGK1). Amiloride 36-45 insulin Homo sapiens 17-24 11684814-6 2001 This effect of insulin was inhibited by amiloride and by staurosporine as well. Amiloride 40-49 insulin Homo sapiens 15-22