PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11751211-5	2002	Exposure of alveolar epithelial cells to amiloride or its analog, 5-(N,N-hexamethylene)-amiloride (HMA), reduced, in a dose-dependent manner, lipopolysaccharide (LPS)-induced secretion of interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha.	Amiloride	41-50	interleukin 1 beta	Homo sapiens	188-210	
12107048-7	2002	NHE inhibition decreased also the IL-1beta-induced HUVEC inflammatory response, because amiloride suppressed IL-1beta-induced E-selectin expression on HUVECs.	Amiloride	88-97	interleukin 1 beta	Homo sapiens	109-117	
27009163-4	2016	IL-1beta elicited an amiloride-sensitive increase in Na(+) transport in taste buds.	Amiloride	21-30	interleukin 1 beta	Homo sapiens	0-8	
27009163-6	2016	The speed and partial amiloride sensitivity of these changes in Na(+) flux indicate that IL-1beta and TNF-alpha modulate epithelial Na(+) channel (ENaC) function.	Amiloride	22-31	interleukin 1 beta	Homo sapiens	89-97	
7524364-6	1994	The enhanced beta-responsiveness produced by IL-1 was eliminated by adding amiloride to block Na+/H+ exchange or protein kinase C inhibitors staurosporine (10 nM) and calphostin C (50 nM).	Amiloride	75-84	interleukin 1 beta	Homo sapiens	45-49	
1443100-2	1992	The amiloride analogue 5-(N-ethyl-N-isopropyl)amiloride (EIPA), an inhibitor of the Na(+)-H+ antiporter, inhibited extracellular IL-1 beta.	Amiloride	4-13	interleukin 1 beta	Homo sapiens	129-138	
1591007-4	1992	In this study, we examine the role of amiloride for the regulation of AM-derived interleukin (IL)-8, tumor necrosis factor (TNF), IL-6, and IL-1 beta.	Amiloride	38-47	interleukin 1 beta	Homo sapiens	140-149	
1591007-7	1992	Furthermore, the suppressive effect of amiloride appeared to be at the level of mRNA for IL-8, TNF, IL-1 beta, and IL-6, whereas steady-state levels of beta-actin mRNA remained unaltered.	Amiloride	39-48	interleukin 1 beta	Homo sapiens	100-109