PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22767612-2	2012	Amiloride was the first organic blocker to selectively block the native T-type calcium channel, but the potency and mechanism of block of this drug on the three recombinant T-type calcium channels (Ca(V)3.1, Ca(V)3.2, and Ca(V)3.3) have not been systematically determined.	Amiloride	0-9	immunoglobulin lambda variable 7-43	Homo sapiens	208-216	
22767612-4	2012	By performing whole-cell patch-clamp recordings of human embryonic kidney 293 cells stably expressing human Ca(V)3 channels, we found that amiloride blocked the human Ca(V)3 channels in a concentration-response manner; the IC50 for Ca(V)3.2 channels (62 muM) was 13-fold lower than that for Ca(V)3.1 and Ca(V)3.3.	Amiloride	139-148	immunoglobulin lambda variable 7-43	Homo sapiens	232-240	
22767612-8	2012	The preferential block of Ca(V)3.2 channels labels amiloride as the only organic blocker to be selective for any T-type channel.	Amiloride	51-60	immunoglobulin lambda variable 7-43	Homo sapiens	26-34