PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31684907-5	2019	RESULTS: Here we demonstrated, in estrogen receptor alpha (ERalpha)-positive breast cancer cells, an androgen-dependent mechanism through which ligand-activated androgen receptor (AR) decreases estradiol-induced cyclin D1 protein, mRNA and gene promoter activity.	Androgens	101-109	estrogen receptor 1	Homo sapiens	34-57	
31821857-5	2020	Mechanistically, these examples call attention to the importance of evolutionary changes in (1) androgen- and estrogen-mediated gene expression, (2) androgen and estrogen receptor expression, and (3) the distribution of androgen and estrogen response elements in target genes throughout the genome.	Androgens	96-104	estrogen receptor 1	Homo sapiens	162-179	
31820173-6	2020	Both estrogen and androgen exert their effects via the estrogen receptor (ER) or the androgen receptor (AR), which belongs to the nuclear receptor superfamily.	Androgens	18-26	estrogen receptor 1	Homo sapiens	55-72	
31820173-6	2020	Both estrogen and androgen exert their effects via the estrogen receptor (ER) or the androgen receptor (AR), which belongs to the nuclear receptor superfamily.	Androgens	18-26	estrogen receptor 1	Homo sapiens	74-76	
31684907-5	2019	RESULTS: Here we demonstrated, in estrogen receptor alpha (ERalpha)-positive breast cancer cells, an androgen-dependent mechanism through which ligand-activated androgen receptor (AR) decreases estradiol-induced cyclin D1 protein, mRNA and gene promoter activity.	Androgens	101-109	estrogen receptor 1	Homo sapiens	59-66	
31966711-2	2017	In this study, the expression of ERbeta was overexpressed in two androgen-independent prostate cancer cell lines, PC-3 and DU145 after transfection with Ad-ERbeta-EGFP virus particles.	Androgens	65-73	estrogen receptor 1	Homo sapiens	33-39	
31966711-7	2017	In conclusion, these results suggest that estrogen may play an important role in androgen-independent prostate cancer cell proliferation through ERbeta-mediated suppression of TGF-beta1/IGF-1.	Androgens	81-89	estrogen receptor 1	Homo sapiens	145-151