PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34069974-6 2021 We showed that PXR knockdown reversed MK-4-mediated stimulation of these genes, indicating the involvement of PXR in this effect. menatetrenone 38-42 nuclear receptor subfamily 1 group I member 2 Homo sapiens 15-18 34069974-6 2021 We showed that PXR knockdown reversed MK-4-mediated stimulation of these genes, indicating the involvement of PXR in this effect. menatetrenone 38-42 nuclear receptor subfamily 1 group I member 2 Homo sapiens 110-113 17875939-9 2007 Knockdown of either PXR or Msx2 attenuated the effect of MK4 on osteoblastic differentiation. menatetrenone 57-60 nuclear receptor subfamily 1 group I member 2 Homo sapiens 20-23 17875939-10 2007 Thus, the present study suggests that Msx2 is a target gene for PXR activated by vitamin K and suggests that the osteoprotective action of MK4 in the human mediates, at least in part, a genomic pathway of vitamin K signaling. menatetrenone 139-142 nuclear receptor subfamily 1 group I member 2 Homo sapiens 64-67