PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12393510-0	2003	A site involving the "hybrid" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia.	Quinine	141-148	integrin subunit beta 3	Homo sapiens	58-64	
12393510-3	2003	We studied a group of quinine-dependent antibodies that react with human glycoprotein IIIa (GPIIIa; beta3-integrin subunit) but fail to recognize rat GPIIIa, despite close homology between the 2 proteins.	Quinine	22-29	integrin subunit beta 3	Homo sapiens	92-98	
12393510-4	2003	By characterizing reactions of these antibodies with human/rat GPIIIa chimeras and selected GPIIIa mutants, we found that each of 3 quinine-dependent antibodies requires a 17-amino acid sequence in the newly recognized "hybrid" and PSI homology domains of GPIIIa for drug-dependent binding.	Quinine	132-139	integrin subunit beta 3	Homo sapiens	63-69	
12393510-4	2003	By characterizing reactions of these antibodies with human/rat GPIIIa chimeras and selected GPIIIa mutants, we found that each of 3 quinine-dependent antibodies requires a 17-amino acid sequence in the newly recognized "hybrid" and PSI homology domains of GPIIIa for drug-dependent binding.	Quinine	132-139	integrin subunit beta 3	Homo sapiens	92-98	
12393510-4	2003	By characterizing reactions of these antibodies with human/rat GPIIIa chimeras and selected GPIIIa mutants, we found that each of 3 quinine-dependent antibodies requires a 17-amino acid sequence in the newly recognized "hybrid" and PSI homology domains of GPIIIa for drug-dependent binding.	Quinine	132-139	integrin subunit beta 3	Homo sapiens	92-98	
12393510-7	2003	The findings suggest this region of GPIIIa may be a favored target for quinine-dependent antibodies and may provide a basis for further studies to elucidate the molecular basis of glycoprotein-drug-antibody interaction.	Quinine	71-78	integrin subunit beta 3	Homo sapiens	36-42	
2363128-0	1990	Expression of the drug-dependent antigen for quinine-dependent antiplatelet antibodies on GP IIIa but not that on GPIb, IIb or IX on human endothelial cells.	Quinine	45-52	integrin subunit beta 3	Homo sapiens	90-97	
2363128-3	1990	By immunoblotting of endothelial cells, quinine-dependent IgG binding from four patient sera was observed only to a 93 kDa component corresponding to GP IIIa.	Quinine	40-47	integrin subunit beta 3	Homo sapiens	150-157	
2363128-5	1990	Thus endothelial cells express the GP IIIa quinine-dependent epitope on platelet GP IIIa, but not those on other platelet glycoproteins.	Quinine	43-50	integrin subunit beta 3	Homo sapiens	35-42	
2363128-5	1990	Thus endothelial cells express the GP IIIa quinine-dependent epitope on platelet GP IIIa, but not those on other platelet glycoproteins.	Quinine	43-50	integrin subunit beta 3	Homo sapiens	81-88