PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24049649-5 2012 Nevertheless, several parameters participating in oxidative stress (increased ROS production and apoptosis, decreased total thiol content) were observed in IB3-1 cells cultured in hypertonic environment as compared to S9 cells and were inhibited by diphenyleneiodonium (DPI), a well-known inhibitor of NOXs; besides, increased production of the proinflammatory cytokines IL-6 and IL-8 by IB3-1 cells was also inhibited by DPI as compared to S9 cells. diphenyleneiodonium 249-268 interleukin 6 Homo sapiens 371-375 30861304-5 2019 Pre-treatment with the ROS inhibitors N-acetyl cysteine (NAC) and diphenyleneiodonium (DPI) partially attenuated CXCL8 and IL-6 responses to 200 microg/mL, but not to 100 microg/mL Si50. diphenyleneiodonium 66-85 interleukin 6 Homo sapiens 123-127 30861304-5 2019 Pre-treatment with the ROS inhibitors N-acetyl cysteine (NAC) and diphenyleneiodonium (DPI) partially attenuated CXCL8 and IL-6 responses to 200 microg/mL, but not to 100 microg/mL Si50. diphenyleneiodonium 87-90 interleukin 6 Homo sapiens 123-127 25961745-8 2015 3-MA, NAC and DPI inhibited HG-induced interleukin-6 production in BMSCs. diphenyleneiodonium 14-17 interleukin 6 Homo sapiens 39-52 11597988-4 2001 We first confirmed that antioxidant N-acetylcysteine, superoxide scavenger Tiron, and DPI suppressed Ang II-induced IL-6 expression. diphenyleneiodonium 86-89 interleukin 6 Homo sapiens 116-120 10826501-9 2000 ET-1-stimulated IL-6 secretion was also suppressed by diphenylene iodonium (40 microM), an inhibitor of flavon-containing enzymes such as NADH/NADPH oxidase. diphenyleneiodonium 54-74 interleukin 6 Homo sapiens 16-20 22305747-8 2012 Exposure of HT-29 colon cancer cells, which express Nox1, to DPI and DTI confirmed their inhibitory effects on steady state ROS levels, and demonstrated decreased Stat, Erk1/2, and Akt signaling mediated by IL-4, IL-6, IL-13, and IL-22, possibly due to a concomitant increase in tumor cell phosphatase activity. diphenyleneiodonium 61-64 interleukin 6 Homo sapiens 213-217