PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31894851-11 2020 Pre-treatment with APS concentration-dependently reversed miR-204 expression, leading to disinhibition of SIRT1 and alleviation of ER stress-induced apoptosis indicated by decreased levels of p-PERK, p-IRE-1, cleaved-ATF6, Bax, cleaved caspase-12, -9, -3, and increased levels of Bcl-2 and unleaved PARP. aps 19-22 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 194-198 33817185-1 2019 Aim: This study investigates the effect of astragalus polysaccharides (APS) in protecting against thapsigargin-induced endoplasmic reticulum (ER) stress in HT29 cells by suppressing the PERK-eIF2a signaling pathway. aps 71-74 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 186-190 33817185-8 2019 Conclusion: The results indicate that APS reduces the expression of GRP78 and CHOP in HT29 cells, at least in part, by preventing the activation of the PERK-eIF2a signaling pathway. aps 38-41 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 152-156