PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33191836-0	2022	Reduction in Tamoxifen Metabolites Endoxifen and N-desmethyltamoxifen With Chronic Administration of Low Dose Cannabidiol: A CYP3A4 and CYP2D6 Drug Interaction.	Cannabidiol	110-121	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	136-142	
33191836-8	2022	CONCLUSION: CBD at a low dose of 40 mg/day resulted in the potential inhibition of CYP3A4 and/or CYP2D6.	Cannabidiol	12-15	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	97-103	
31433338-7	2019	The isoforms CYP2D6, CYP2C19, CYP2B6, and CYP2J2 are inhibited by THC and CBD.	Cannabidiol	74-77	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	13-19	
21704641-7	2011	Seven of 14 recombinant human CYP enzymes examined (CYP1A1, CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5) were capable of metabolizing CBD.	Cannabidiol	142-145	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	85-91	
21821735-0	2011	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Cannabidiol	0-11	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	74-80	
21821735-5	2011	CBD competitively inhibited the CYP2D6 activities with the apparent K(i) values of 1.16 to 2.69 muM.	Cannabidiol	0-3	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	32-38	
21821735-6	2011	To clarify the structural requirement for CBD-mediated CYP2D6 inhibition, effects of CBD-related compounds on the AMMC O-demethylase activity of recombinant CYP2D6 were examined.	Cannabidiol	42-45	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	55-61	
21821735-6	2011	To clarify the structural requirement for CBD-mediated CYP2D6 inhibition, effects of CBD-related compounds on the AMMC O-demethylase activity of recombinant CYP2D6 were examined.	Cannabidiol	42-45	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	157-163	
34491040-7	2021	Since CYP2D6 is an important brain and liver P450 and is known to be inhibited by CBD, we investigated the interactions of four important highly prevalent CYP2D6 polymorphisms with selected phytocannabinoids (CBD, THC, CBDV, THCV, CBN, CBG, CBC, beta-carophyllene) that are rapidly gaining popularity.	Cannabidiol	82-85	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	6-12