PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28601556-4	2017	The mRNA levels of microphthalmia-associated transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP) 1, and TRP2 were increased following cannabidiol treatment.	Cannabidiol	156-167	melanocyte inducing transcription factor	Homo sapiens	19-65	
28601556-5	2017	Likewise, cannabidiol increased the protein levels of MITF, TRP 1, TRP 2, and tyrosinase.	Cannabidiol	10-21	melanocyte inducing transcription factor	Homo sapiens	54-58	
28601556-6	2017	Mechanistically, we found that cannabidiol regulated melanogenesis by upregulating MITF through phosphorylation of p38 mitogen-activated protein kinase (MAPK) and p42/44 MAPK, independent of cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) signaling.	Cannabidiol	31-42	melanocyte inducing transcription factor	Homo sapiens	83-87	
28601556-8	2017	Taken together, these findings indicate that cannabidiol-induced melanogenesis is cannabinoid CB1 receptor-dependent, and cannabidiol induces melanogenesis through increasing MITF gene expression which is mediated by activation of p38 MAPK and p42/44 MAPK.	Cannabidiol	122-133	melanocyte inducing transcription factor	Homo sapiens	175-179	
28601556-4	2017	The mRNA levels of microphthalmia-associated transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP) 1, and TRP2 were increased following cannabidiol treatment.	Cannabidiol	156-167	melanocyte inducing transcription factor	Homo sapiens	67-71