PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25652132-11 2015 Mechanistically, roflumilast N-oxide when combined with dexamethasone increased the expression of MKP1, and enhanced the inhibitory effects on phospho-p38, AP1 and NFkappaB activities which may explain the additive anti-inflammatory effects. n-oxide 29-36 nuclear factor kappa B subunit 1 Homo sapiens 164-172