PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23348515-2 2013 Previously, two exon 11 small deletions, c.1699_1670DeltaAT (DeltaAT) and c.1706_1709DeltaAGTG (DeltaAGTG), that prematurely truncated or elongated the ALAS2 polypeptide, were reported to increase enzymatic activity 20- to 40-fold, causing the erythroid accumulation of protoporphyrins, cutaneous photosensitivity and liver disease. Protoporphyrins 270-285 5'-aminolevulinate synthase 2 Homo sapiens 152-157