PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15006396-1 2004 Recently, we reported a novel substrate-based octapeptide BACE1 inhibitor KMI-008 containing hydroxymethylcarbonyl (HMC) isostere as a transition-state mimic. hydroxymethylcarbonyl 93-114 beta-secretase 1 Homo sapiens 58-63