PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28854431-9	2017	RESULTS: Iopromide caused elevation of SCr, BUN and NGAL level, decrease of endogenous creatinine clearance, morphological injury and tubular apoptosis, enhanced IL-1beta and IL-18 expression, and increased expression of S100A8/A9, TLR4 and NLRP3 inflammsome.	iopromide	9-18	NLR family, pyrin domain containing 3	Rattus norvegicus	241-246	
28854431-10	2017	In NRK-52E cells, iopromide caused enhanced apoptotic rates and ROS generation, which could be ameliorated by inhibitor of TLR4 and NLRP3-siRNA.	iopromide	18-27	NLR family, pyrin domain containing 3	Rattus norvegicus	132-137