PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34681898-13 2021 In conclusion, the data suggested that ardisianone induced the apoptosis and pyroptosis of leukemic cells through downregulation of IAPs and activation of caspase pathways that caused gasdermin D cleavage and DNA double-stranded breaks and ultimately led to programmed cell death. Ardisianone 39-50 gasdermin D Homo sapiens 184-195