PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34341510-0	2022	ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome.	ML365	0-5	NLR family, pyrin domain containing 3	Mus musculus	50-55	
34341510-9	2022	We showed that ML365 (1, 5 muM) concentration-dependently inhibited ATP-induced NLRP3 inflammasome activation in LPS-primed murine BMDMs, whereas it did not affect nigericin-induced NLRP3, or non-canonical, AIM2 and NLRC4 inflammasomes activation.	ML365	15-20	NLR family, pyrin domain containing 3	Mus musculus	80-85	
34341510-10	2022	Knockdown of TWIK2 significantly impaired the inhibitory effect of ML365 on ATP-induced NLRP3 inflammasome activation.	ML365	67-72	NLR family, pyrin domain containing 3	Mus musculus	88-93