PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11880503-2 2002 In pheochromocytoma cells, MMT exposure resulted in rapid increase in generation of reactive oxygen species (ROS) within 5--15 min, followed by release of mitochondrial cytochrome C into cytoplasm and subsequent activation of cysteine proteases, caspase-9 (twofold to threefold) and caspase-3 (15- to 25-fold), but not caspase-8, in a time- and dose-dependent manner. 2-methylcyclopentadienyl manganese tricarbonyl 27-30 caspase 9 Homo sapiens 246-255